The Effect of Cerebellar Transcranial Direct Current Stimulation on A Throwing Task Depends on Individual Level of Task Performance
The Effect of Cerebellar Transcranial Direct Current Stimulation on A Throwing Task Depends on Individual Level of Task Performance
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DOI：
10.1016/j.neuroscience.2017.11.048
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发表时间：
2018-02-10
期刊：
影响因子：
3.3
通讯作者：
Kanosue, Kazuyuki
中科院分区：
文献类型：
--
作者：
Mizuguchi, Nobuaki;Katayama, Takashi;Kanosue, Kazuyuki
小脑经颅直流电刺激（tDCS）对运动表现的影响仍存在争议。一些研究表明，经颅直流电刺激 (tDCS) 的效果取决于任务难度和个人任务表现水平。在这里，我们研究了小脑 tDCS 对运动表现的影响是否取决于个人的表现水平。 24 名天真的参与者在不同的日子里练习投飞镖，同时在三种刺激条件（阳极、阴极和假 tDCS）下接受 2-mA 小脑 tDCS 20 分钟，采用双盲、平衡交叉设计。通过测量靶心中心与飞镖位置之间的距离来评估任务表现。尽管在所有刺激条件下，任务绩效在整个练习过程中都会有所提高，但与第一个无刺激块相比，在一天内的改善并不显着。此外，刺激条件之间的改善没有差异。然而，改善的程度仅在阴极 tDCS 条件下与个体的任务表现水平相关（p < 0.05）。与假 tDCS 相比，仅表现水平较低的参与者亚组的表现出现显着改善 (p < 0.05)。这些发现表明，小脑阴极 tDCS 对复杂全身运动的运动技能学习的促进作用取决于个人的任务表现水平。因此，小脑 tDCS 仅有助于一小部分人学习复杂的运动技能任务。 (C) 2017 年国际广播组织。由爱思唯尔有限公司出版。保留所有权利。
The effect of cerebellar transcranial direct current stimulation (tDCS) on motor performance remains controversial. Some studies suggest that the effect of tDCS depends upon task-difficulty and individual level of task performance. Here, we investigated whether the effect of cerebellar tDCS on the motor performance depends upon the individual's level of performance. Twenty-four naive participants practiced dart throwing while receiving a 2-mA cerebellar tDCS for 20 min under three stimulus conditions (anodal-, cathodal-, and sham-tDCS) on separate days with a double-blind, counter-balanced cross-over design. Task performance was assessed by measuring the distance between the center of the bull's eye and the dart's position. Although task performance tended to improve throughout the practice under all stimulus conditions, improvement within a given day was not significant as compared to the first no-stimulus block. In addition, improvement did not differ among stimulation conditions. However, the magnitude of improvement was associated with an individual's level of task performance only under cathodal tDCS condition (p < 0.05). This resulted in a significant performance improvement only for the sub-group of participants with lower performance levels as compared to that with sham-tDCS (p < 0.05). These findings suggest that the facilitation effect of cerebellar cathodal tDCS on motor skill learning of complex whole-body movements depends on the level of an individual's task performance. Thus, cerebellar tDCS would facilitate learning of a complex motor skill task only in a subset of individuals. (C) 2017 IBRO. Published by Elsevier Ltd. All rights reserved.