LAMINAR ORGANIZATION OF FREQUENCY-DEFINED LOCAL AXONS WITHIN AND BETWEEN THE INFERIOR COLLICULI OF THE GUINEA-PIG
LAMINAR ORGANIZATION OF FREQUENCY-DEFINED LOCAL AXONS WITHIN AND BETWEEN THE INFERIOR COLLICULI OF THE GUINEA-PIG
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DOI：
10.1002/cne.903570112
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发表时间：
1995-06-19
影响因子：
2.5
通讯作者：
BJAALIE, JG
中科院分区：
文献类型：
--
作者：
MALMIERCA, MS;REES, A;BJAALIE, JG
本文对豚鼠下丘中央核（CNICs）的局部（内在和连合）联系进行了全面的描述。将顺行示踪剂biocytin局部注射到CNIC的生理学上确定的位点中，并用计算机辅助三维（3-D）重建揭示了标记纤维的空间组织。每个椎板神经丛有一个位于CNIC的中央翼，延伸到背侧皮质和一个位于外皮质的外翼。两翼相交的边缘界定了中央核与外部皮质的外侧边界。标记终端的密度始终低于在皮质比在CNIC。椎板丛连接CNIC内频率相似的点。在三维视图中，椎板丛的位置、方向、形状和面积随最佳频率而变化。终止于注射对侧IC的连合纤维也形成与同侧神经丛对称的层状神经丛。电解病变放置在对侧IC的网站与最佳频率相对应的注射相吻合的连合纤维的终端在大多数情况下。这些连接的组织（点到点和发散）的可能模式进行了讨论。三个系统的外周轴突的层流丛进行了描述：平行，斜，和垂直于中央翼。新颖的并联系统在两个IC中具有平行于中央翼的端子。它可能构成跨频率相互作用的解剖学基础。斜向和垂直系统分别是投射到IC连合和臂的通道纤维。(C)1995年Wiley-Liss，Inc.
We present a comprehensive description of the local (intrinsic and commissural) connections in the central nucleus of the inferior colliculi (CNICs) in guinea pig. Focal injections of the anterograde tracer biocytin were made into physiologically identified loci of the CNIC and the spatial organisation of the labeled fibres was revealed with computer-assisted three-dimensional (3-D) reconstruction.The intrinsic fibres form a series of V-shaped laminar plexuses composed of fibres bearing both terminal and en passant boutons. Each laminar plexus has a central wing located in the CNIC that extends into the dorsal cortex and an external wing located in the external cortex. The edge where the two wings intersect delimits the lateral border of the central nucleus with the external cortex. The density of labeled terminals was consistently lower in the cortices than in the CNIC. The laminar plexus connects points of similar frequency within the CNIC. Seen in 3-D, the location, orientation, shape, and area of the laminar plexus vary as a function of best frequency. The commissural fibres ending in the contralateral IC to the injection also form a laminar plexus which is symmetrical to the ipsilateral plexus. Electrolytic lesions placed in the contralateral IC at sites with best frequencies corresponding to those of the injection coincided with the terminals of the commissural fibres in most instances. Possible patterns for the organisation of these connections (point-to-point and diverging) are discussed.Three systems of peripheral axons to the laminar plexus are described: parallel, oblique, and perpendicular to the central wing. The novel parallel system has terminals in both ICs that run parallel to the central wing. It might constitute the anatomical basis for across-frequency interactions. The oblique and perpendicular systems are fibres of passage projecting to the commissure and brachium of the IC, respectively. (C) 1995 Wiley-Liss, Inc.