HYDRA TRANSPLANTATION PHENOMENA AND THE MECHANISM OF HYDRA HEAD REGENERATION .2. PROPERTIES OF THE HEAD ACTIVATION
HYDRA TRANSPLANTATION PHENOMENA AND THE MECHANISM OF HYDRA HEAD REGENERATION .2. PROPERTIES OF THE HEAD ACTIVATION
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DOI：
10.1016/0012-1606(83)90325-1
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发表时间：
1983-01-01
影响因子：
2.7
通讯作者：
MACWILLIAMS, HK
中科院分区：
文献类型：
--
作者：
MACWILLIAMS, HK
测量了九头蛇组织移植碎片的头部激活。测量结果证实，头部的激活在体内是分级的，并且在头部再生过程中激活会增加。两种不同类型的实验表明，再生特异性激活增加仅限于假定的头部区域。当头部形成被启动并随后被阻断时，激活在.apprx中衰减回其原始水平。12 h;这比在移动到更基础位置的身体组织中观察到的激活衰减快3倍。足部形成现象的实验也显示出类似的不稳定性差异。再生特异性激活增加可能涉及的机制不同于负责体内激活梯度的机制。切割产生头部和/或足部激活水平的局部增加；这种增长在大约10年内衰减。这些结果和其他结果与Gierer-Meinhardt模型的一个版本一致，该模型也解释了九头蛇头/体比例的调节。
Measurements were made of the head activation in transplanted fragments of Hydra tissue. The measurements confirm that head activation is graded in the body and that activation increases during head regeneration. Experiments of 2 different sorts show that regeneration-specific activation increase is confined to the presumptive head zone. When head formation is initiated and subsequently blocked, the activation decays back to its original level in .apprx. 12 h; this is 3 times faster than the activation decay observed in body tissue moved to a more basal position. Experiments on foot formation phenomena show a similar lability difference. Regeneration-specific activation increase probably involves a mechanism different from the one responsible for the gradient of activation in the body. Cutting produces a local increase of the head and/or foot activation level; this increase decays in .apprx. 12 h. These results and others are consistent with a version of the Gierer-Meinhardt model which also accounts for the regulation of the head/body proportion in Hydra.