Management of Burkitt's lymphoma: an update.

Management of Burkitt's lymphoma: an update.
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伯基特淋巴瘤的治疗:更新。

DOI:
10.1016/s0305-7372(79)80044-4
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发表时间:
1979
影响因子:
11.8
通讯作者:
J. Ziegler
J. Ziegler
中科院分区:
医学1区
文献类型:
--
作者:
J. Ziegler

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伯基特淋巴瘤是人类生长最快的肿瘤。因此,早期诊断、并发症意识和治疗策略知识是成功结果的关键因素。由于50%以上的患者可治愈该病,因此应尽一切治疗努力实现这一目标。由于这种疾病的侵袭性,几乎没有时间对诊断或悠闲的分期过程提出异议。最后,虽然这种疾病在美国很少见,但伯基特淋巴瘤仍然为基于肿瘤动力学的治疗策略提供了一个有用的临床模型。例如,对耐药复发的积极管理已经在被认为无望的临床情况下产生了持久的完全反应。来自伯基特淋巴瘤的治疗原理应该成功地应用于人类的其他肿瘤,以开发旨在治愈的药物方案。
Burkitt's lymphoma is the fastest growing neoplasm in man. As such, early diagnosis, awareness of complications, and knowledge of therapeutic strategy are critical factors in a successful outcome. Since the disease is curable in over 50% of patients, every therapeutic effort should be applied to this objective. Because of the aggressive nature of the disease, there is little time for demurring over the diagnosis or a leisurely staging process. Finally, though the disease is rare in the U.S.A., Burkitt's lymphoma continues to provide a useful clinical model for therapeutic strategy based on tumor kinetics. For example, aggressive management of drug resistant relapse has yielded durable complete responses in clinical situations which were considered hopeless. Therapeutic principles derived from Burkitt's lymphoma should be successfully applied to other neoplasms of man in developing drug regimens aimed at cure.
DOI: --
发表时间: 1971-11
期刊: Cancer research
影响因子: 11.2
作者:
P. Carbone;H. Kaplan;K. Musshoff;D. Smithers;M. Tubiana
通讯作者: P. Carbone;H. Kaplan;K. Musshoff;D. Smithers;M. Tubiana