Stretch magnitude and frequency-dependent actin cytoskeleton remodeling in alveolar epithelia
Stretch magnitude and frequency-dependent actin cytoskeleton remodeling in alveolar epithelia
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DOI：
10.1152/ajpcell.00379.2009
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发表时间：
2010-08-01
影响因子：
5.5
通讯作者：
Margulies, Susan S.
中科院分区：
文献类型：
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作者：
DiPaolo, Brian C.;Lenormand, Guillaume;Margulies, Susan S.
DiPaolo BC、Lenormand G、Fredberg JJ、Margulies SS。肺泡上皮细胞的拉伸幅度和频率依赖性肌动蛋白细胞骨架重塑。 Am J Physiol Cell Physiol 299：C345-C353，2010。首次发表于 2010 年 6 月 2 日； doi: 10.1152/ajpcell.00379.2009.-肺泡上皮细胞 (AEC) 通过内部固定在肌动蛋白细胞骨架上的垫圈状细胞间紧密连接 (TJ) 维持血气屏障的完整性。我们假设拉伸会快速重组肌动蛋白（
DiPaolo BC, Lenormand G, Fredberg JJ, Margulies SS. Stretch magnitude and frequency-dependent actin cytoskeleton remodeling in alveolar epithelia. Am J Physiol Cell Physiol 299: C345-C353, 2010. First published June 2, 2010; doi: 10.1152/ajpcell.00379.2009.-Alveolar epithelial cells (AEC) maintain integrity of the blood-gas barrier with gasket-like intercellular tight junctions (TJ) that are anchored internally to the actin cytoskeleton. We hypothesize that stretch rapidly reorganizes actin (