Effects of early parenting on growth and development in a small primate
Effects of early parenting on growth and development in a small primate
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DOI：
10.1203/00006450-199606000-00012
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发表时间：
1996-06-01
影响因子：
3.6
通讯作者：
Chrousos, GP
中科院分区：
文献类型：
--
作者：
Johnson, EO;Kamilaris, TC;Chrousos, GP
我们在这里报告了一项研究，研究了照顾者-婴儿关系对一种小型灵长类动物——普通狨猴的身体生长和行为发育的影响。通过测量未麻醉猴子的体重、膝跟长度、头尾长度、头围和雌性阴部垫宽度或雄性睾丸体积来评估体细胞生长。通过焦点动物样本收集离散饲养行为的行为信息。我们的数据表明，当猴子达到10周龄和20周龄时，婴儿期积极父母行为的频率与身高相关。此外，我们发现幼年期被父母虐待的幼鱼在体重、膝跟长度和头尾长度上都较小，并且表现出异常的社会行为。最后，为了解决在幼年动物中观察到的生长明显下降是否也与下丘脑-垂体-肾上腺（HPA）轴功能的改变有关，我们检查了这些动物对合成促肾上腺皮质激素释放激素（oCRH）的血浆ACTH和皮质醇反应。我们发现一种小型灵长类动物，即普通狨猴，对外源性皮质醇的增量反应。通过测量体重、膝后跟长度、在婴儿期经历过消极父母教育的年轻成年人的体细胞生长oCRH明显低于那些没有父母虐待的人，表明这些动物的下丘脑-垂体-肾上腺轴功能发生了改变。我们的研究结果表明，父母照顾的质量会影响年幼狨猴的成长和行为。
We report here a study of the impact of caregiver-infant relationships on physical growth and behavioral development in a small primate, the common marmoset. Somatic growth was assessed from measurements of body weight, knee-heel length, head-tail length, head circumference, and pudendal pad width in females or testis volume in males obtained from unanesthetized monkeys. Behavioral information was gathered by focal animal samples for discrete rearing behaviors. Our data suggest that the frequency of positive parental behaviors during infancy is correlated with stature when the monkeys reach 10 and 20 wk of age. Furthermore, we found that juveniles that were mistreated by their parents during infancy were smaller in body weight, knee-heel length, and head-tail length, and they demonstrated abnormal social behavior. Finally, to address whether the apparent decreased growth observed in the young animals that had experienced negative parenting was also associated with alterations in hypothalamic-pituitary-adrenal (HPA) axis function, we examined the plasma ACTH and cortisol responses to synthetic ovine corticotropin-releasing hormone (oCRH) in these animals. relationships on physical growth and behavioral development in We found that the incremental cortisol response to exogenous a small primate, the common marmoset. Somatic growth was oCRH was significantly lower in the young adults that had assessed from measurements of body weight, knee-heel length, experienced negative parenting during infancy compared with those who bad nonabusive parents, indicating altered hypothalamic-pituitary-adrenal axis function in these animals. Our findings suggest that the quality of parental care influences later growth and behavior in the young marmoset.