Immunoblastic sarcoma in donor cells after bone-marrow transplantation.
Immunoblastic sarcoma in donor cells after bone-marrow transplantation.
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骨髓移植后供体细胞中的免疫母细胞肉瘤。
DOI：
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发表时间：
1979
影响因子：
158.5
通讯作者：
C. Taylor
中科院分区：
文献类型：
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作者：
T. Gossett;R. Gale;H. Fleischman;G. Austin;R. Sparkes;C. Taylor
人类淋巴瘤的发病机制尚不清楚。多种因素与动物淋巴瘤诱导相关，包括免疫抑制、免疫刺激、自身免疫、抑制性T淋巴细胞功能丧失、逆转录病毒感染、药物和辐射。宿主疾病、内源性C型RNA病毒的激活、自身免疫和易感小鼠的淋巴瘤。4，5在人类中，一系列免疫相关疾病与恶性淋巴瘤有关。这些疾病包括干燥综合征、类风湿性关节炎、多动脉炎、系统性红斑狼疮和各种其他自身免疫性疾病。此外，在接受免疫抑制治疗的患者中，肾移植患者，有明显增加......
THE pathogenesis of lymphomas in man is unknown. A variety of factors are associated with lymphoma induction in animals, including immuno-suppression, immune stimulation, autoimmunity, loss of suppressor T-lymphocyte function, retravirus infection, drugs and irradiation.1 2 3 Recently several workers have reported an association between graft-vs.-host disease, activation of endogenous C-type RNA viruses, autoimmunity and lymphomas in susceptible mice.4 , 5 In man, a spectrum of immune-related disorders have been associated with malignant lymphomas. These diseases include Sjogren's syndrome, rheumatoid arthritis, polyarteritis, systemic lupus erythematosus and various other autoimmune disorders. Furthermore, in patients receiving immunosuppressive therapy, recipients of renal transplants, there is a marked increase . . .