Prior cycling exercise does not prevent endothelial dysfunction after resistance exercise
Prior cycling exercise does not prevent endothelial dysfunction after resistance exercise
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DOI：
10.1007/s00421-019-04154-1
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发表时间：
2019-07-01
影响因子：
3
通讯作者：
Ochi, Eisuke
中科院分区：
文献类型：
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作者：
Morishima, Takuma;Toyoda, Masahira;Ochi, Eisuke
目的抗阻运动对血管内皮功能有急性损伤作用。因此，设计一种有效的策略来预防抗阻运动后急性内皮功能障碍变得非常重要。在这里，我们测试的假设，阻力运动引起的颞叶内皮功能障碍是防止由先前cycling.MethodsTwelve年轻健康受试者完成两个随机实验性试验：（1）阻力运动只试验（RE试验），（2）阻力运动与先前的自行车试验（C+RE试验）。基线肱动脉血流介导的扩张（FMD）后，受试者在RE试验中保持仰卧位45分钟;受试者在C+RE试验中进行45分钟的骑自行车（67.01.7% HRmax）。受试者在休息或骑车45 min后，在相同时间点进行抗阻运动（69.74.0 kg）。抗阻训练结束后，要求受试者仰卧位休息60 min。结果抗阻运动后血流动力学改变无显著性差异，仰卧位休息60 min后血流动力学改变消失。在%FMD反应中没有显著的相互作用。两项试验均引起抗阻运动后%FMD的降低，RE试验中抗阻运动后30 min和60 min的%FMD降低有统计学意义。结论抗阻运动前骑自行车45 min不足以预防抗阻运动后急性内皮功能障碍。
PurposeResistance exercise impairs endothelial function acutely. Therefore, it becomes important to devise an effective strategy for preventing acute endothelial dysfunction after resistance exercise. Herein, we tested the hypothesis that resistance exercise-induced temporal endothelial dysfunction is prevented by prior cycling.MethodsTwelve young healthy subjects completed two randomized experimental trials: (1) resistance exercise only trial (RE trial), (2) resistance exercise with prior cycling trial (C+RE trial). Following baseline brachial artery flow-mediated dilation (FMD), the subjects maintained the supine position for 45min in the RE trial; the subjects performed a 45min of cycling (67.01.7% HRmax) in the C+RE trial. After 45min of resting or cycling, the subjects performed resistance exercise (69.74.0kg) at the same time points. Following the resistance exercise, they were asked to rest in the supine position for 60min. Then FMD were repeated at 10, 30 and 60min after the resistance exercise in both trials.Results The increased blood flow and shear rate after resistance exercise did not differ between trials, and these changes disappeared following resting in the supine position for 60min. There was no significant interaction in %FMD responses. Both trials caused impairment in %FMD after the resistance exercise, and statistical significance was observed at 30 and 60min after resistance exercise in the RE trial.Conclusion The present study revealed that cycling for 45min prior to resistance exercise was not sufficient to prevent the acute endothelial dysfunction after resistance exercise.