Impaired Error-Monitoring Function in People with Internet Addiction Disorder: An Event-Related fMRI Study
Impaired Error-Monitoring Function in People with Internet Addiction Disorder: An Event-Related fMRI Study
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DOI：
10.1159/000346783
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发表时间：
2013-01-01
影响因子：
3.9
通讯作者：
Du, Xiaoxia
中科院分区：
文献类型：
--
作者：
Dong, Guangheng;Shen, Yue;Du, Xiaoxia
背景：网络成瘾障碍（IAD）正迅速成为世界范围内普遍存在的精神健康问题。应该研究IAD的神经生物学基础，以揭示潜在的异质性。本研究旨在探讨IAD受试者的错误监测能力。方法：15名IAD患者和15名健康对照（HC）参与本研究。参与者被要求执行一个可能显示错误反应的快速Stroop任务。比较了IAD和HC受试者在错误反应方面的行为和神经生物学结果。结果：与HC相比，IAD受试者在错误反应后，前扣带皮层（ACC）的激活增加，眶额皮质的激活减少。ACC激活与网络成瘾测试成绩显著相关。结论：与HC相比，IAD受试者的错误监测能力受损，这可以通过错误反应中ACC的过度激活来检测。版权所有：巴塞尔S. kager AG
Background: Internet addiction disorder (IAD) is rapidly becoming a prevalent mental health concern around the world. The neurobiological underpinnings of IAD should be studied to unravel the potential heterogeneity. This study was set to investigate the error-monitoring ability in IAD subjects. Methods: Fifteen IAD subjects and 15 healthy controls (HC) participated in this study. Participants were asked to perform a fast Stroop task that may show error responses. Behavioral and neurobiological results in relation to error responses were compared between IAD subjects and HC. Results: Compared to HC, IAD subjects showed increased activation in the anterior cingulate cortex (ACC) and decreased activation in the orbitofrontal cortex following error responses. Significant correlation was found between ACC activation and the Internet addiction test scores. Conclusions: IAD subjects show an impaired error-monitoring ability compared to HC, which can be detected by the hyperactivation in ACC in error responses. Copyright (c) 2013 S. Karger AG, Basel