Temporal trends in the age-specific prevalence of diabetes and diabetic retinopathy in older persons: Population-based survey findings
Temporal trends in the age-specific prevalence of diabetes and diabetic retinopathy in older persons: Population-based survey findings
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DOI：
10.1016/j.diabres.2006.04.002
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发表时间：
2006-12-01
影响因子：
5.1
通讯作者：
Wang, Jie Jin
中科院分区：
文献类型：
--
作者：
Cugati, Sudha;Kifley, Annette;Wang, Jie Jin
目的：比较 6 年来糖尿病和糖尿病视网膜病变 (DR) 的特定年龄患病率。方法：蓝山眼科研究 (BMES) 在 BMES 1 (19921994) 中对 3654 名年龄 > 49 岁的居民（82.4% 响应）进行了调查。幸存者 (n = 2335) 和新符合条件的居民 (n = 1174) 在 BMES II (1997-2000) 中接受了检查。糖尿病的定义是病史或空腹血糖>= 7.0 mmol/L。使用艾尔利屋分类法根据 6 视野视网膜照片对 DR 进行分级。由于每个年龄组的样本都是独立的，因此比较了 5 年间隔的特定年龄患病率。结果：总体糖尿病患病率从 7.8% 增加至 9.9% (p = 0.002)，而 60-74 岁年龄组的特定年龄患病率在 6 年内增加。与 BMES I 相比，BMES 11 中轻度 DR 的患病率略高（p = 0.018），但中重度 DR 的患病率较低（p = 0.049）。与 DR 患病率显着相关的因素是糖尿病病程 >= 20 年（BMES I，OR 7.6 [2.9-20.5]；BMES II，OR 6.1） [2.5-15.4]）和血糖水平（每 mmol/L 增加 BMES 1，OR 1.1 [1.0-1.2]；BMES II，OR 1.2 [1.1-1.3]）。结论：在 6 年来来自同一地区的两项调查样本中，糖尿病患病率有所增加，但严重 DR 患病率有所下降。 (c) 2006 Elsevier Ireland Ltd. 保留所有权利。
Purpose: To compare the age-specific prevalence of diabetes and diabetic retinopathy (DR) over 6 years. Methods: The Blue Mountains Eye Study (BMES) examined 3654 residents (82.4% response) aged > 49 years in BMES 1 (19921994). Survivors (n = 2335) and newly eligible residents (n = 1174) were examined in BMES II (1997-2000). Diabetes was defined by history or fasting plasma glucose >= 7.0 mmol/L. DR was graded from 6-field retinal photographs using the Airlie House Classification. Age-specific prevalence in 5-year intervals was compared, as samples of each age group were independent. Results: The overall diabetes prevalence increased from 7.8 to 9.9% (p = 0.002) while the age-specific prevalence increased in age groups 60-74 years, over 6 years. A slightly higher prevalence of mild levels of DR (p = 0.018) but lower prevalence of moderate-severe levels of DR (p = 0.049) was evident in BMES 11 compared to BMES I. Factors significantly associated with DR prevalence were diabetes duration >= 20 years (BMES I, OR 7.6 [2.9-20.5]; BMES II, OR 6.1 [2.5-15.4]) and blood glucose level (BMES 1, OR 1.1 [1.0-1.2]; BMES II, OR 1.2 [1.1-1.3] per mmol/L increase). Conclusions: An increased prevalence of diabetes, but decreased prevalence of severe levels of DR, was documented in two survey samples from the same region over 6 years. (c) 2006 Elsevier Ireland Ltd. All rights reserved.