The effects of thimerosal, a sulfhydryl reagent, on phasic myometrial contractions.
The effects of thimerosal, a sulfhydryl reagent, on phasic myometrial contractions.
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硫柳汞（一种硫氢基试剂）对阶段性子宫肌层收缩的影响。
DOI：
10.1006/bbrc.1995.1769
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Phillippe,M
中科院分区：
文献类型：
--
作者：
Phillippe,M
硫柳汞抑制钙的摄取和IP 3诱导的钙从IP 3敏感的内质网释放;本研究旨在评估硫柳汞对激动剂刺激的阶段性子宫肌层收缩的影响。发现噻吗替尼显著抑制催产素、氟化铝、氯化钾、离子霉素和Bay K 8644刺激的阶段性收缩。这些观察结果为钙摄取和IP 3诱导的钙释放是激动剂刺激的阶段性子宫肌层收缩过程中的重要事件这一假设提供了支持。
Thimerosal inhibits calcium uptake and IP3-induced calcium release from IP3-sensitive endoplasmic reticulum; this study sought to evaluate the effects of thimerosal on agonist-stimulated phasic myometrial contractions. Thimerosal was found to significantly inhibit phasic contractions stimulated by oxytocin, aluminum fluoride, potassium chloride, ionomycin, and Bay K 8644. These observations provide support for the hypothesis that calcium uptake and IP3-induced calcium release are important events during agonist-stimulated phasic myometrial contractions.