Trends in levels of cholesterol in Japanese children from 1993 through 2001.
Trends in levels of cholesterol in Japanese children from 1993 through 2001.
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DOI：
10.2188/jea.14.78
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发表时间：
2004-05
影响因子：
4.7
通讯作者：
Takeuchi H
中科院分区：
文献类型：
--
作者：
Kouda K;Nakamura H;Tokunaga R;Takeuchi H
背景：儿童的心血管危险因素增加了日后患心血管疾病的可能性。我们试图确定日本儿童心血管危险因素的当前趋势。方法：从1993年到2001年，我们每年对日本岩田市所有小学的五年级学生进行调查。我们检查了4,673名男孩和4,484名女孩，年龄在10-11岁。测量身高、体重、体重指数和血清总胆固醇浓度。采用回归分析方法对趋势进行评估。自变量是考试的历年。因变量为每个个体的人体测量值和血清总胆固醇浓度。还检查了年份与高脂血症患病率和肥胖症患病率的关系。结果：女生身高、男女体重均与年龄呈正相关。女孩和男孩的体重指数也显示出与日历年的正相关关系。此外，肥胖症患病率也有所上升。在胆固醇水平方面，男女总胆固醇浓度与年份呈正相关。此外，高脂血症的患病率也有所增加。结论：这些结果表明，在过去的十年中，参与研究的日本儿童的体重指数和血清总胆固醇浓度都有所增加。
BACKGROUND: Cardiovascular risk factors in children raise the possibility of cardiovascular disease later in life. We attempted to determine the current trends in cardiovascular risk factors among Japanese children. METHODS: We examined fifth-graders at all the elementary schools in Iwata city in Japan every year from 1993 through 2001. We examined 4,673 boys and 4,484 girls, aged 10-11 years. Height, body weight, body mass index, and serum total cholesterol concentrations were measured. Regression analysis was used to evaluate the trends. The independent variable was the calendar year of the examination. The dependent variables were the anthropometric values and the serum total cholesterol concentration in each individual. The relationships between the year and the prevalence of hyperlipidemia and the prevalence of obesity were also examined. RESULTS: Both the heights of the girls and the body weights of the both sexes were positively associated with the year. The body mass index in both girls and boys also showed positive relationships with the calendar year. In addition, there was an increase in the prevalence of obesity. Concerning the levels of cholesterol, positive regression coefficients were shown between the total cholesterol concentration and the year in both sexes. Furthermore, there was an increase in prevalence of hyperlipidemia. CONCLUSION: These results indicate that during the past decade among Japanese children involved in the study, both the body mass index and the serum total cholesterol concentrations increased.