LUNG AND CHEST WALL COMPLIANCE OF APNEIC PARALYZED INFANTS
LUNG AND CHEST WALL COMPLIANCE OF APNEIC PARALYZED INFANTS
复制标题
呼吸暂停瘫痪婴儿的肺和胸壁顺应性
DOI：
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发表时间：
1961
影响因子：
15.9
通讯作者：
L. Bachman
中科院分区：
文献类型：
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作者：
C. C. Richards;L. Bachman
已发现麻醉放松成人的总呼吸顺应性值低于清醒受试者（1，2）。对这一事实的可能解释是，有意识的个体不能像麻醉的病人那样完全放松。因此，在无意识受试者中观察到的值更接近需要人工呼吸的麻醉患者（1，2）或通过机械呼吸器通气的未麻醉的呼吸暂停脊髓灰质炎患者（3）的值。通过使用身体体积描记器和食管内压力技术测量了静息新生儿的肺顺应性（4，5）。当以肺重量为基础与成人记录的值进行比较时，这些值较低。然而，由于肺顺应性与功能性残气量密切相关（4，6，7），在此基础上对婴儿和成人肺进行比较表明，它们的顺应性相似。我们一直未能找到任何报告的测量总肺和胸壁的顺应性在麻醉，瘫痪的婴儿。这是我们奋进获得这些信息的报告，我们相信，这将提供更好地了解婴儿呼吸生理学。这些数据对婴儿复苏、麻醉和婴儿复苏器的设计也有实际意义。
The total respiratory compliance of anesthetized, relaxed adults has been found to have a lower value than that in awake subjects (1, 2). The probable explanation for this fact is the inability of the conscious individual to relax as completely as does the anesthetized patient. The values observed in unconscious subjects, therefore, more closely approximate those of narcotized patients in need of artificial respiration (1, 2) or of unanesthetized, apneic polio patients being ventilated by a mechanical respirator (3). The pulmonary compliance of resting newborn infants has been measured by the use of a body plethysmograph and intraesophageal pressure technique (4, 5). These values are low when compared on a lung weight basis to those recorded for the adult. However, since lung compliance relates closely to the functional residual capacity (4, 6, 7), a comparison of infant and adult lungs on this basis suggests that they are similar in compliance. Wehave been unable to find any report of measurements of total lung and chest wall compliance in the anesthetized, paralyzed infant. This is a report of our endeavor to obtain such information, which, we believe, will provide a better understanding of infant respiratory physiology. These data also are of practical interest for infant resuscitation, anesthesia, and in the design of infant resuscitators.