Olfactory functioning and callosotomy: a report of two cases.

Olfactory functioning and callosotomy: a report of two cases.
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嗅觉功能和胼胝体切开术:两例报告。

DOI:
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发表时间:
1988
期刊:
The Yale Journal of Biology and Medicine
影响因子:
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通讯作者:
R. Novelly
R. Novelly
中科院分区:
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文献类型:
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作者:
Brenda Eskenazi;William S. Cain;E. Lipsitt;R. Novelly

文献摘要

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两个胼胝体切开术患者与假定完整的前连合进行了评估,对电池的嗅觉任务,包括敏感性,歧视,记忆,识别,跨模态匹配,双边总和(dirhinic与monorhinic阈值),和本地化的气味。1例病例在术前和术后均进行了评价。手术后,他的气味记忆和跨模式匹配明显下降。手术后,两名患者都能更好地命名气味呈现给左鼻孔比右鼻孔。被要求记住容易标记的气味的患者能够更好地记住呈现在左丘脑的气味。无论嗅觉和触觉信息是投射到同一个半球还是不同的半球,这两个病例的表现都一样好,一些双边的总和是明显的,并且这些病例无法定位气味,这表明剩下的神经通路允许半球之间的一些交流。
Two callosotomy patients with presumably intact anterior commissures were evaluated on a battery of olfactory tasks including sensitivity, discrimination, memory, identification, cross-modality matching, bilateral summation (dirhinic vs. monorhinic thresholds), and localization of odorants. One case was evaluated both pre- and post-surgery. He showed marked decrements after surgery in odor memory and in matching across modalities. After surgery, both patients were better able to name odorants presented to the left nostril than the right nostril. The patient who was asked to remember odorants that could be readily labeled was better able to remember those odorants presented to the left nostril. The findings that both cases performed equally well whether olfactory and tactile information was projected to the same hemisphere or a different one, that some bilateral summation was evident, and that the cases were unable to localize odorants suggests that the remaining neuronal pathways allow for some communication between hemispheres.