PRE-SPINAL CONVERGENCE BETWEEN THORACIC AND VISCERAL NERVES OF THE RAT

PRE-SPINAL CONVERGENCE BETWEEN THORACIC AND VISCERAL NERVES OF THE RAT
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DOI:
10.1016/0304-3940(92)90493-q
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发表时间:
1992-04-13
影响因子:
2.5
通讯作者:
PIERAU, FK
PIERAU, FK
中科院分区:
医学4区
文献类型:
--
作者:
DAWSON, NJ;SCHMID, H;PIERAU, FK

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感觉轴突的二分性在许多物种中都已被证实,这对理解牵涉痛的可能机制具有重要意义。 本研究综述了工作采用荧光染料作为示踪剂,以证明传入的二分法在周围神经系统。 用二脒基黄或固蓝的神经内转运方法证明了大鼠肋间神经和内脏神经的二分性。 脊髓前躯体-内脏会聚频率平均为2%(范围0.1-21%)。 肋间内、外神经的平均会聚频率为8.3%(范围2-23.1%)。 长春碱抑制轴浆运输的对照实验排除了标记物非轴浆运输错误的可能性。 胸内脏脊髓前会聚发生在大鼠,是可变的程度。
Dichotomizing sensory axons have been demonstrated in a number of species and are of significance in understanding the possible mechanisms underlying referred pain. The present study reviews work employing fluorescent dyes as tracers to demonstrate afferent dichotomization in the peripheral nervous system. Dichotomization between the intercostal and splanchnic nerves of the rat was demonstrated by means of intraneural transport of Diamidino yellow or Fast blue. Frequency of pre-spinal somato-visceral convergence averaged 2% (range 0.1-21%). Average frequency of convergence was 8.3% (range 2-23.1%) between internal and external intercostal nerves. Control experiments in which axoplasmic transport was inhibited by vinblastine ruled out the possibility of errors from non-axoplasmic transport of the markers. Thoraco-visceral pre-spinal convergence occurs in the rat and is variable in extent.