CASE-CONTROL STUDY OF RELATIONSHIPS OF DIET AND OTHER TRAITS TO COLORECTAL CANCER IN AMERICAN BLACKS
CASE-CONTROL STUDY OF RELATIONSHIPS OF DIET AND OTHER TRAITS TO COLORECTAL CANCER IN AMERICAN BLACKS
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DOI：
10.1093/oxfordjournals.aje.a112668
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发表时间：
1979-01-01
影响因子：
5
通讯作者：
WILLIAMS, SR
中科院分区：
文献类型：
--
作者：
DALES, LG;FRIEDMAN, GD;WILLIAMS, SR
对来自医院和多相健康检查诊所的99名黑人结直肠癌患者和280名匹配的对照者进行了关于过去饮食习惯和其他特征的访谈。结肠癌病例倾向于报告使用至少0.5%纤维含量的食物的频率低于对照组。这种关系虽然很小，但表现出一致的剂量-反应梯度，出现在病例-医院对照和病例-多相健康检查对照比较中，并且不能被其他变量的影响所解释。结肠和直肠乙状结肠连接部癌症患者倾向于比对照组更经常地食用含有至少5%饱和脂肪的食物。当这两组食物的消费被认为是在组合中，显着更多的结肠癌患者比对照组报告了高饱和脂肪食物低纤维食物的饮食模式，而不是低饱和脂肪食物高纤维食物的饮食。结直肠癌患者还报告了以下特征的统计学显著过度：男性长期吸烟，女性未生育和结直肠息肉病史。
Black colorectal cancer patients (99) and 280 matched controls from hospitals and multiphasic health checkup clinics were interviewed about past dietary habits and other traits. The colon cancer cases tended to report less frequent use of foods with at least 0.5% fiber content than did their controls. This relationship, though small, showed a consistent dose-response gradient, appeared in case-hospital control and case-multiphasic health checkup control comparisons and could not be accounted for by the effects of other variables. Colon and rectosigmoid junction cancer patients tended to have eaten foods with at least 5% saturated fat somewhat more often than controls. When consumption of these 2 groups of foods was considered in combination, significantly more colon cancer patients than controls reported a high saturated fat foods-low fibrous foods eating pattern, as opposed to a low saturated fat foods-high fibrous foods diet. Statistically significant excesses of the following traits were also reported by the colorectal cancer patients: prolonged cigar smoking in men, nulliparity in women and history of colorectal polyps.