Preschool outcomes of children of depressed mothers: Role of maternal behavior, contextual risk, and children's brain activity
Preschool outcomes of children of depressed mothers: Role of maternal behavior, contextual risk, and children's brain activity
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DOI：
10.1111/1467-8624.00599
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发表时间：
2003-07-01
影响因子：
4.6
通讯作者：
Embry, L
中科院分区：
文献类型：
--
作者：
Dawson, G;Ashman, SB;Embry, L
抑郁母亲的孩子面临行为和情感问题的风险。抑郁母亲的婴儿表现出行为障碍和非典型的额叶脑活动。儿童产生这种脆弱性的机制尚不清楚。研究人员对母亲有（N = 65）和无（N = 59）抑郁病史的三岁儿童的行为问题和脑电活动进行了评估。与没有抑郁症的母亲和抑郁症缓解的母亲的孩子相比，患有慢性抑郁症的母亲的孩子表现出较低的额叶和顶叶脑激活。抑郁的母亲报告了更高的背景风险（例如，婚姻不和谐和压力），并且她们的孩子有更多的行为问题。儿童额叶脑激活和情境风险水平介导了母亲抑郁和儿童行为问题之间的关系。
Children of depressed mothers are at risk for behavioral and emotional problems. Infants of depressed mothers exhibit behavioral disturbances and atypical frontal brain activity. The mechanisms by which children develop such vulnerabilities are not clear. Three-year-old children of mothers with (N = 65) and without (N = 59) a history of depression were assessed in terms of behavior problems and brain electrical activity. Children of mothers with chronic depression exhibited lower frontal and parietal brain activation compared with children of mothers without depression and those whose depression remitted. Depressed mothers reported higher contextual risk (e.g., marital discord and stress) and their children had more behavior problems. Children's frontal brain activation and contextual risk level mediated the relation between maternal depression and child behavior problems.