3D steerable, acoustically powered microswimmers for single-particle manipulation
3D steerable, acoustically powered microswimmers for single-particle manipulation
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DOI：
10.1126/sciadv.aax3084
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发表时间：
2019-10-01
期刊：
影响因子：
13.6
通讯作者：
Mallouk, Thomas E.
中科院分区：
文献类型：
--
作者：
Ren, Liqiang;Nama, Nitesh;Mallouk, Thomas E.
以非接触、生物相容的方式精确操纵流体中的微/纳米物体的能力可以实现创新技术，并可能在生物学、化学工程和纳米技术等领域产生深远的影响。在这里，我们报告了一个设计的声学供电的气泡为基础的microswimmer，能够自主运动在三维空间和选择性地运输个人的合成胶体和哺乳动物细胞在一个拥挤的群体没有标签，表面修饰，或对附近的物体的影响。与先前报道的微型游泳者相比，它们的运动不需要在声压节点处操作，从而能够在低功率和远离超声换能器的情况下推进。在兆赫的声场中，微泳者受到两种主要的力：次级Bjerknes力和局部产生的声流推进力。这两种力的结合使得微型游泳者能够在三维边界上或在磁操纵下在自由空间中独立地游泳。
The ability to precisely maneuver micro/nano objects in fluids in a contactless, biocompatible manner can enable innovative technologies and may have far-reaching impact in fields such as biology, chemical engineering, and nanotechnology. Here, we report a design for acoustically powered bubble-based microswimmers that are capable of autonomous motion in three dimensions and selectively transporting individual synthetic colloids and mammalian cells in a crowded group without labeling, surface modification, or effect on nearby objects. In contrast to previously reported microswimmers, their motion does not require operation at acoustic pressure nodes, enabling propulsion at low power and far from an ultrasonic transducer. In a megahertz acoustic field, the microswimmers are subject to two predominant forces: the secondary Bjerknes force and a locally generated acoustic streaming propulsive force. The combination of these two forces enables the microswimmers to independently swim on three dimensional boundaries or in free space under magnetical steering.