Parathyroid tumors.

Parathyroid tumors.
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DOI:
10.1007/s11864-003-0007-x
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发表时间:
2003-08-01
影响因子:
4.3
通讯作者:
Udelsman, Robert
Udelsman, Robert
中科院分区:
医学2区
文献类型:
--
作者:
Carling, Tobias;Udelsman, Robert

文献摘要

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引起原发性甲状旁腺功能亢进的甲状旁腺肿瘤很常见,尽管大多数患者的诊断性检查并不复杂,但仍经常无法诊断。患者往往得不到适当的治愈性治疗,即手术治疗。最近的研究表明,手术对轻度无症状疾病的患者是有益的,特别是在骨疾病、神经心理症状和血脂异常的逆转方面。所有患有这种疾病的患者都应该转诊给内分泌外科医生,以讨论手术干预。在门诊环境中进行的微创技术发展迅速,并显示出极高的成功率,低发病率,并可能成为大多数原发性甲状旁腺功能亢进患者的标准治疗。
Parathyroid tumors causing primary hyperparathyroidism are common and often remain undiagnosed, despite that the diagnostic work-up is uncomplicated in most patients. The patients often do not receive the appropriate curative treatment, which is surgical. Recent studies show that surgery is beneficial in patients with mild asymptomatic disease, especially in the reversal of bone disease, neuropsychologic symptoms, and dyslipoproteinemia. All patients with the disease deserve a referral to an endocrine surgeon for discussions regarding surgical intervention. Minimally invasive techniques performed in the ambulatory setting have evolved rapidly and show an extraordinary high success rate, low-morbidity rate, and are likely to become the standard treatment for most patients with primary hyperparathyroidism.