Supply-demand balance and metabolic scaling
Supply-demand balance and metabolic scaling
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DOI：
10.1073/pnas.162216899
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发表时间：
2002-08-06
影响因子：
11.1
通讯作者：
Rinaldo, A
中科院分区：
文献类型：
--
作者：
Banavar, JR;Damuth, J;Rinaldo, A
人们普遍认为，在大多数（如果不是所有）生物体中，代谢率在物种间的比例约为质量的3/4次方。因此，每单位质量的代谢需求随着体重的增加而减少。代谢率反映了生物体的运输系统将代谢物输送到组织的能力以及组织使用代谢物的速率。我们发现，无处不在的3/4幂定律种间代谢缩放产生于简单的，一般的几何性质的运输网络约束功能的生物有机体。3/4指数和其他观察到的标度关系遵循时，特定质量的代谢需求相匹配的网络在不同的身体大小的不断变化的交付能力。与3/4指数的偏离表明效率低下或补偿生理机制。我们的结论是基于一般性的论点，包含了最少的生物学细节，因此应该适用于最广泛的生物体。
It is widely accepted that metabolic rates scale across species approximately as the 3/4 power of mass in most if not all groups of organisms. Metabolic demand per unit mass thus decreases as body mass increases. Metabolic rates reflect both the ability of the organism's transport system to deliver metabolites to the tissues and the rate at which the tissues use them. We show that the ubiquitous 3/4 power law for interspecific metabolic scaling arises from simple, general geometric properties of transportation networks constrained to function in biological organisms. The 3/4 exponent and other observed scaling relationships follow when mass-specific metabolic demands match the changing delivery capacities of the network at different body sizes. Deviation from the 3/4 exponent suggests either inefficiency or compensating physiological mechanisms. Our conclusions are based on general arguments incorporating the minimum of biological detail and should therefore apply to the widest range of organisms.