Direct evidence for preferential multiplication ofBabesia gibsoni in young erythrocytes
Direct evidence for preferential multiplication ofBabesia gibsoni in young erythrocytes
复制标题
吉氏巴贝虫在年轻红细胞中优先增殖的直接证据
DOI：
10.1007/bf00932180
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发表时间：
2004
影响因子：
2
通讯作者：
Y. Maede
中科院分区：
文献类型：
--
作者：
T. Murase;M. Iwai;Y. Maede
阐明宿主红细胞年龄对巴贝虫寄生虫繁殖的影响，B.吉布索尼与网织红细胞、未成熟红细胞或来自狗的成熟红细胞一起培养。在未成熟红细胞培养物中，寄生虫血症在培养第8天达到峰值水平(34.1%±15.8%)，而在成熟细胞培养物中达到的最高寄生虫血症仅在第5天达到3.6%±2.2%。这些结果清楚地表明B.吉布氏寄生虫优先侵入年轻红细胞而不是成熟细胞并在其中繁殖。
To clarify the effect of the age of host erythrocytes on the multiplication ofBabesia parasites,B. gibsoni was cultured together with reticulocytes, immature erythrocytes, or mature erythrocytes from dogs. Parasitemia reached peak levels (34.1%±15.8%) at cultivation day 8 in immature-erythrocyte culture, whereas the highest parasitemia attained in mature-cell culture was only 3.6%±2.2% at day 5. These results clearly demonstrate thatB. gibsoni parasites preferentially invade and multiply in young erythrocytes rather than in mature cells.
影响因子：
20.3
作者：
CHASIS, JA;PRENANT, M;MOHANDAS, N
通讯作者：
MOHANDAS, N