Anxiolytics reduce residual dizziness after successful canalith repositioning maneuvers in benign paroxysmal positional vertigo
Anxiolytics reduce residual dizziness after successful canalith repositioning maneuvers in benign paroxysmal positional vertigo
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DOI：
10.3109/00016489.2011.637179
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发表时间：
2012-03-01
影响因子：
1.4
通讯作者：
Song, Jae-Jin
中科院分区：
文献类型：
--
作者：
Jung, Hahn Jin;Koo, Ja-Won;Song, Jae-Jin
结论：本研究提示辅助抗焦虑药物对良性阵发性位置性眩晕(BPPV)患者可能是有帮助的，即使在成功地完成了导管结石复位术(CRP)之后。目的：尽管CRP是治疗BPPV的一种有效方法，但许多患者在CRPS成功后仍持续头晕。本研究的目的是评估辅助性抗焦虑药物对CRP成功后残留头晕的影响。方法：2011年1月至2011年3月，73例BPPV患者接受CRPS治疗。患者被随机分配到药物组或对照组。药物组给予小剂量依替唑仑治疗2周，对照组不给予任何药物治疗。所有患者均在主观视觉垂直评估后2周复诊。采用头晕残障量表(DHI)和活动特定平衡信任度(ABC)量表对CRP治疗前后的主观症状进行评定。结果：两组患者的DHI评分均有显著改善。然而，药物组在功能(p=0.018)和情绪(p=0.030)分量表以及总的DHI分(p=0.038)方面的下降幅度明显更大。
Conclusions: This study suggests that adjuvant anti-anxiety medication may be helpful for patients with benign paroxysmal positional vertigo (BPPV) even after a successful canalith repositioning procedure (CRP). Objective: Although the CRP is an effective treatment for BPPV, many patients suffer from persistent dizziness despite successful CRPs. The aim of this study was to evaluate the effect of adjuvant anxiolytic medication on residual dizziness after successful CRP. Methods: Between January 2011 and March 2011, 73 patients were diagnosed with BPPV and they underwent successful treatment with CRPs. The patients were randomly assigned to either the medication group or the control group. The patients in the medication group were prescribed low dose etizolam for 2 weeks whereas the patients in the control group were not prescribed any medication. All patients were scheduled to return 2 weeks after evaluation of subjective visual vertical. Subjective symptoms before and after CRP were measured using the Dizziness Handicap Inventory (DHI) and the Activities-specific Balance Confidence (ABC) scale. Results: Both groups demonstrated a significant improvement in DHI scores. However, the medication group showed significantly greater decrease in the functional (p = 0.018) and emotional (p = 0.030) subscale scores, as well as in the total DHI (p = 0.038) score.