Magnetic separation techniques: their application to medicine
Magnetic separation techniques: their application to medicine
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DOI：
10.1007/bf00220980
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发表时间：
1985-05
影响因子：
4.3
通讯作者：
Dr. J. T. Kemsheadl;J. Ugelstad
中科院分区：
文献类型：
--
作者：
Dr. J. T. Kemsheadl;J. Ugelstad
虽然依靠重力的分离技术在生物学上的应用已经变得相对复杂，但磁分离过程却并非如此。后者的使用仅限于少数含有顺磁性铁的电池。然而，随着几种不同类型的磁性粒子和选择性递送系统(如单抗)的发展，磁分离技术的使用正在迅速增长。本文综述了目前可用的不同类型的颗粒，应用于不同磁性化合物的磁分离技术，并说明了目前磁分离程序在生物和医学领域中的主要用途。
Whilst separation techniques relying on gravitational forces have become relatively sophisticated in their application to biology the same is not true for magnetic separation procedures. The use of the latter has been limited to the few cells which contain paramagnetic iron. However with the development of several different types of magnetic particles and selective delivery system (e.g. monoclonal antibodies) the use of magnetic separation techniques is growing rapidly. This review describes the different types of particles currently available, the magnetic separation technique applied to the different magnetic compounds and illustrates major uses to which magnetic separation procedures are currently applied in the area of biology and medicine.