DNA‐Wrapped Single Walled Carbon Nanotubes as Rigid Templates for Assembling Linear Gold Nanoparticle Arrays
DNA‐Wrapped Single Walled Carbon Nanotubes as Rigid Templates for Assembling Linear Gold Nanoparticle Arrays
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DOI：
10.1002/adma.200602861
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发表时间：
2007-06
影响因子：
29.4
通讯作者：
Xiaogang Han;Yulin Li;Z. Deng
中科院分区：
文献类型：
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作者：
Xiaogang Han;Yulin Li;Z. Deng
该通信报告了一种将金纳米颗粒（AuNPs）组装到DNA包裹的单壁碳纳米管（SWNTs）上的策略。自1991年首次报道以来，碳纳米管一直是深入研究的主题。[1]到目前为止，许多研究人员一直致力于探索其独特的物理和化学性质。[2]尽管它们具有非常吸引人的特性，但所制备的碳纳米管的溶解性差通常是许多应用的障碍。已经进行了各种研究工作，以便通过化学接枝[3]或通过在碳纳米管上吸附小分子或聚合物分子的亲水层[4]来获得水溶性碳纳米管。Zheng等人发现，具有特定碱基序列的DNA单链具有非常强的缠绕SWNT的倾向，因此可以在超声处理下帮助将SWNT分散在水溶液中。[5]这一发现鼓励研究人员进一步完善这项技术，并为这些DNA包裹的碳纳米管找到新的特性和应用。[6]由于其易于合成和表面改性，以及其良好的生物相容性和表面光学特性，金纳米颗粒已被广泛用作模型系统，以展示新的自组装策略，如纳米级构建块的集成。DNA具有可编程的自组装能力，是组装金纳米粒子的理想超分子材料。[7-10]到目前为止，工程DNA纳米结构已成功地用作支架，将金纳米颗粒组织成明确的2D晶格以及微米长的线性阵列。[11尽管DNA代表了用于材料的程序化组装的理想模板，但是当用于组装多价物体时，所形成的结构的柔性通常会引起诸如卷曲、自缠结、甚至自交联的问题。通过使用特别设计的交叉结构[13]或通过在亚基上对齐线性DNA分子来增加其刚性的努力，
This communication reports a strategy toward the assembly of gold nanoparticles (AuNPs) onto DNA-wrapped singlewalled carbon nanotubes (SWNTs). Carbon nanotubes have been the subject of intensive research since they were first reported in 1991.[1] So far, a lot of researchers have been directed to probe their unique physical and chemical properties.[2] Despite their very attractive properties, the poor solubility of as-prepared carbon nanotubes is often one obstacle ahead of many applications. Various research works have been carried out in order to obtain water-soluble carbon nanotubes either by chemical grafting [3] or by adsorbing a hydrophilic layer of small or polymeric molecules [4] on the carbon nanotubes. Zheng et al. have found that DNA single strands with specific base sequences have a very strong tendency to wrap around SWNTs and thus can help to disperse SWNTs in aqueous solutions under sonication.[5] This finding has encouraged researchers to further refine the technique and to find new properties and applications for these DNA-wrapped carbon nanotubes.[6]Because of their easy synthesis and surface modification, as well as their good biocompatibility and surface optical properties, gold nanoparticles have been widely used as a model system to demonstrate new self-assembly strategies developed toward applications such as integration of nanoscaled building blocks. DNA has been found to be an ideal supramolecular material for the assembly of gold nanoparticles mainly due to its programmable self-assembly ability.[7–10] So far, engineered DNA nanostructures have been successfully used as scaffolds to organize gold nanoparticles into well-defined 2D lattices as well as micrometer-long linear arrays.[11, 12] Although DNA represents an ideal template for the programmed assembly of materials, the flexibility of the formed structures often causes problems such as curling, self-entangling, and even self-crosslinking when used to assemble multivalent objects. Efforts to increase its rigidity by using specially designed crossover structures [13] or by aligning linear DNA molecules on a sub-