Race-ethnicity-specific waist circumference cutoffs for identifying cardiovascular disease risk factors.
Race-ethnicity-specific waist circumference cutoffs for identifying cardiovascular disease risk factors.
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DOI：
10.1093/ajcn.81.2.409
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发表时间：
2005-02
期刊：
影响因子：
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通讯作者：
Shankuan Zhu;S. Heymsfield;H. Toyoshima;Zimian Wang;A. Pietrobelli;S. Heshka
中科院分区：
文献类型：
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作者：
Shankuan Zhu;S. Heymsfield;H. Toyoshima;Zimian Wang;A. Pietrobelli;S. Heshka
背景白人男性和女性的腰围(WCs)代表心血管疾病(CVD)的风险相当于身体质量指数(BMI；以公斤/平方米为单位)的25和30。然而，其他种族群体的厕所界限仍然未知。目的确定非西班牙裔黑人(黑人)、墨西哥裔美国人(MA)和非西班牙裔白人(白人)心血管疾病风险的WC临界值。对第三次国民健康与营养调查(1988-1994)的10,969名受试者的设计资料进行了分析。心血管疾病危险因素的存在是主要结果。使用Logistic回归模型，根据超重和肥胖的BMI界值，将WC界值与相当的心血管疾病风险联系起来，以确定性别和种族特定的WC界值。代谢综合征危险因素的WC临界值计算方法类似。结果各组腰围与血脂、血压、血糖的相关性均显著高于体重指数与这些变量的相关性。在体重指数在25到40之间时，白人的腰围界限大约比黑人大5-6厘米，而马萨诸塞州的腰围界限是中等的。在女性中，观察到两组之间的厕所截止值几乎没有差异。与年龄基本无关的BMI为25和30的3个种族组的简化腰围界限分别为男性和101厘米，女性83厘米和94厘米。当使用WC截止值而不是BMI截止值时，接收器工作特性曲线的最小距离往往较短。结论在所研究的3个种族群体中，WC是比BMI更好的心血管风险指标。在预测心血管疾病风险方面，建议的WC临界值比BMI临界值更敏感。
BACKGROUND Waist circumferences (WCs) in white men and women that represent a risk of cardiovascular disease (CVD) equivalent to that of body mass indexes (BMIs; in kg/m2) of 25 and 30 have been identified. However, WC cutoffs for other race-ethnicity groups remain unknown. OBJECTIVE The objective was to determine WC cutoffs for CVD risk in non-Hispanic blacks (blacks), Mexican Americans (MA), and non-Hispanic whites (whites). DESIGN Data from 10,969 participants in the third National Health and Nutrition Examination Survey (1988-1994) were analyzed. The presence of CVD risk factors was the main outcome. Sex- and race-ethnicity-specific WC cutoffs were determined with logistic regression models by linking WC cutoffs with equivalent CVD risk based on BMI cutoffs for overweight and obesity. WC cutoffs for metabolic syndrome risk factors were similarly calculated. RESULTS Correlations between WC and lipid profiles, blood pressure, and glucose were significantly higher than those between BMI and these same variables in all groups. The WC cutoffs were approximately 5-6 cm greater for white than for black men at BMIs between 25 and 40, and those for MA were intermediate. In women, few differences in WC cutoffs were observed between the groups. Simplified WC cutoffs corresponding to BMIs of 25 and 30, largely independent of age, for the 3 race-ethnicity groups were 89 and 101 cm for men and 83 and 94 cm for women. Minimal distances in receiver operating characteristic curves tended to be shorter when WC cutoffs rather than BMI cutoffs were used. CONCLUSIONS WC is a better indicator of CVD risk than is BMI in the 3 race-ethnicity groups studied. The proposed WC cutoffs are more sensitive than are BMI cutoffs in predicting CVD risk.