Vitamin B1 deficiency in patients with postural tachycardia syndrome (POTS)
Vitamin B1 deficiency in patients with postural tachycardia syndrome (POTS)
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DOI：
10.1080/01616412.2017.1331895
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发表时间：
2017-01-01
影响因子：
1.9
通讯作者：
Blitshteyn, Svetlana
中科院分区：
文献类型：
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作者：
Blitshteyn, Svetlana
目的：POTS是一种异质性自主神经系统疾病，可由多种病因引起。在POTS患者中观察到维生素B12、维生素D 25-OH和铁缺乏症的患病率增加。本研究探讨了维生素B1缺乏症的患病率，并评估了对维生素B1补充剂在缺乏POTS patients.Methods和Results的反应：65例连续POTS患者在我们的诊所进行了评估的医疗记录进行了审查。在这个队列（平均年龄32岁，范围13- 54岁，89%的女性），6%的维生素B1缺乏症，和四个缺乏患者之一经历了显着改善POTS口服维生素B1 supplementation.Conclusion：一个小子集的POTS患者可能有维生素B1缺乏症。建议测试维生素B1缺乏症并纠正缺乏症。
Objective: POTS is a heterogeneous disorder of the autonomic nervous system that can result from multiple etiologies. An increased prevalence of vitamin B12, vitamin D 25-OH and iron deficiencies has been observed in patients with POTS. This study examined the prevalence of vitamin B1 deficiency and assessed response to vitamin B1 supplementation in the deficient POTS patients.Methods and Results: Medical records of 65 consecutive patients with POTS evaluated at our clinic were reviewed. In this cohort (mean age 32, range 13-54years; 89% female), 6% had vitamin B1 deficiency, and one of four deficient patients experienced significant improvement of POTS after oral vitamin B1 supplementation.Conclusion: A small subset of patients with POTS may have vitamin B1 deficiency. Testing for vitamin B1 deficiency and correcting the deficiency is recommended.