Recent advances in nanostructure/nanomaterial-assisted laser desorption/ionization mass spectrometry of low molecular mass compounds
Recent advances in nanostructure/nanomaterial-assisted laser desorption/ionization mass spectrometry of low molecular mass compounds
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DOI:
10.1016/j.aca.2019.08.048
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发表时间:
2019-12-20
影响因子:
6.2
通讯作者:
Liu, Zhen
中科院分区:
文献类型:
--
作者:
He, Hui;Guo, Zhanchen;Liu, Zhen
Laser desorption ionization mass spectrometry (LDI-MS) has been developed to be an essential tool for the analysis and identification of a large variety of species, ranging from small metabolites, drugs and pollutants to peptides and proteins and even to bacteria. Matrix assisted LDI-MS has shown a great power for macromolecules, but its analytical capability to low mass compounds is limited due to inherent drawbacks, including abundant interference in low mass range (