Accessing genomic data through XML-based remote procedure calls

Accessing genomic data through XML-based remote procedure calls
复制标题

通过基于 XML 的远程过程调用访问基因组数据

DOI:
--
复制
发表时间:
2002
期刊:
American Medical Informatics Association Annual Symposium
影响因子:
--
通讯作者:
I. Kohane
I. Kohane
中科院分区:
--
文献类型:
--
作者:
A. Riva;I. Kohane

文献摘要

参考文献

相似文献

随着公共基因组数据库中数据量的增长,它们之间的互操作性正成为一个越来越重要的特征。自动化系统挖掘和整合数据的能力对于从数据源中提取知识至关重要,这些数据源的数量远远超过人类研究人员的能力。目前的主流模式是将信息呈现为Web页面,并使用超链接来描述信息片段之间的关系,这种模式有利于可用性,但却使互操作性和自动数据交换变得更加困难。在本文中,我们描述了如何SNPper,基于Web的单核苷酸多态性(SNP)的检索和分析系统,增强了远程过程调用接口,允许客户端应用程序查询我们的程序SNP数据,并接收响应作为一个XML文档。以这种形式表示的数据可以很容易地被请求程序解析,从而可以被其他应用程序重用。在本文中,我们描述了接口的实现,我们展示了它的使用在一些现有的应用程序的例子。
As the amount of data in public genomic databases grows, interoperability among them is becoming an increasingly critical feature. The ability for automated systems to mine and integrate data will be crucial to extracting knowledge from sources of data whose volume far exceeds the capabilities of human researchers. The currently dominant paradigm of presenting information as Web pages and using hyperlinks to describe relationships between pieces of information favors usability, but makes interoperability and automated data exchange more difficult. In this paper we describe how SNPper, a web-based system for the retrieval and analysis of Single Nucleotide Polymorphisms (SNPs), was augmented with a Remote Procedure Call interface, allowing client applications to query our program for SNP data and to receive the response as an XML document. Data represented in this form can be easily parsed by the requesting program, and thus reused for other applications. In this paper we describe the implementation of the interface and we show examples of its usage in a number of existing applications.
DOI: 10.1126/science.280.5366.1077
发表时间: 1998-05-15
期刊: SCIENCE
影响因子: 56.9
作者:
Wang, DG;Fan, JB;Lander, ES
通讯作者: Lander, ES