Surgical Management and Prognostic Prediction of Adenocarcinoma of Jejunum and Ileum.
Surgical Management and Prognostic Prediction of Adenocarcinoma of Jejunum and Ileum.
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空肠和回肠腺癌的手术治疗和预后预测
DOI：
10.1038/s41598-017-15633-w
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发表时间：
2017-11-09
影响因子：
4.6
通讯作者：
Zhang H
中科院分区：
文献类型：
--
作者：
Xie X;Zhou Z;Song Y;Dang C;Zhang H
我们进行了一项回顾性研究，基于监测，流行病学和最终结果计划（SEER）数据库，建立一个新的诺模图预后预测系统，并估计总生存率和预后因素之间的关系，以及探讨空回肠腺癌的外科治疗策略。本研究共纳入了来自SEER数据库的883例患者。八个潜在的预后因素包括在列线图模型和判别力和准确性进行了检查，使用Harrell的C指数和赤池信息标准（AIC）指数。与AJCC TNM分期系统相比，诺模图预测系统的准确性和均匀性更高（Harrell的C指数，0.731 vs. AIC指数为4852.9vs. 4913.723）。对于外科治疗，切除超过12个局部淋巴结可以提高生存的可能性。本研究表明，我们的诺模图模型比传统的AJCC TNM分期系统更准确，更均匀，适当的肠系膜淋巴结清扫术手术策略可提高总生存率。
We conducted a retrospective study based on the Surveillance, Epidemiology, and End Results Program (SEER) database to establish a novel nomogram prognostic prediction system and to estimate the association between overall survival and prognostic factors, as well as to explore surgical treatment strategies for adenocarcinoma of the jejunum and ileum. A total of 883 patients from the SEER database were included in this study. Eight potential prognostic factors were included in a nomogram model and discriminatory power and accuracy were examined using the Harrell’s C-index and Akaike Information Criterion (AIC) index. In comparison with the AJCC TNM staging system, the nomogram prediction system was more accurate and homogeneous (Harrell’s C-index, 0.731vs. 0.667; AIC index, 4852.9vs. 4913.723). For surgical management, resection of more than 12 local lymph nodes could improve the likelihood of survival. This study demonstrates that our nomogram model is more accurate and homogeneous than the traditional AJCC TNM staging system, and proper surgical strategies for mesenteric lymphadenectomy improve overall survival.
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DOI：
10.6004/jnccn.2013.0022
发表时间：
2013-02-01
影响因子：
13.4
作者：
Benson, Al B., III;Bekaii-Saab, Tanios;Freedman-Cass, Deborah A.
通讯作者：
Freedman-Cass, Deborah A.
影响因子：
6.2
作者：
Dabaja, BS;Suki, D;Ajani, J
通讯作者：
Ajani, J
影响因子：
16.6
作者：
Li, Jie;Lenferink, Anne E. G.;Deng, Yinghai;Collins, Catherine;Cui, Qinghua;Purisima, Enrico O.;O'Connor-McCourt, Maureen D.;Wang, Edwin
通讯作者：
Wang, Edwin
DOI：
10.1016/s1470-2045(14)71116-7
发表时间：
2015-04
期刊：
The Lancet. Oncology
影响因子：
--
作者：
Balachandran VP;Gonen M;Smith JJ;DeMatteo RP
通讯作者：
DeMatteo RP
影响因子：
9.6
作者：
Landerholm, K.;Zar, N.;Jarhult, J.
通讯作者：
Jarhult, J.