Behavioral Signatures of a Developing Neural Code
Behavioral Signatures of a Developing Neural Code
复制标题
DOI：
10.1016/j.cub.2020.06.040
复制
发表时间：
2020-09-07
期刊：
影响因子：
9.2
通讯作者：
Goodhill, Geoffrey J.
中科院分区：
文献类型：
--
作者：
Avitan, Lilach;Pujic, Zac;Goodhill, Geoffrey J.
在生命的早期，神经编码必须发展，以适当地将感觉输入转换为行为输出。在这里，我们展示了视觉大脑中神经编码的成熟度与视觉引导行为的发育变化之间的联系。在斑马鱼幼体中，我们发现视觉驱动的捕食行为在受精后4至15天有所改善，变得更快、更准确。在同一时期，视顶盖部分的种群活动得到改善，改善了特定空间位置的解码和信息传输。值得注意的是，解码过程中的个体差异可以预测每条鱼的狩猎成功。总而言之，这些结果有助于揭示自然行为所需的神经代码是如何在发育过程中出现的。
During early life, neural codes must develop to appropriately transform sensory inputs into behavioral outputs. Here, we demonstrate a link between the maturity of neural coding in the visual brain and developmental changes in visually guided behavior. In zebrafish larvae, we show that visually driven hunting behavior improves from 4 to 15 days post-fertilization, becoming faster and more accurate. During the same period, population activity in parts of the optic tectum refines, improving decoding and information transmission for particular spatial positions. Remarkably, individual differences in decoding can predict each fish's hunting success. Together, these results help reveal how the neural codes required for a natural behavior emerge during development.