Strong effects of heterosis on the evolution of dispersal rates
Strong effects of heterosis on the evolution of dispersal rates
复制标题
杂种优势对扩散率演变的强烈影响
DOI：
--
复制
发表时间：
2009
影响因子：
2.1
通讯作者：
François Rousset
中科院分区：
文献类型：
--
作者：
Denis Roze;Denis Roze;François Rousset
当扩散受到限制时，不同区域之间的杂交可能产生比区域内杂交更高适合度的后代，这是由于来自同一区域的个体更可能共享相同的隐性有害等位基因。这种现象（称为杂种优势）产生了有利于分散的选择力;然而，杂种优势对分散进化的重要性一直是争论的主题。在本文中，我们使用计算机模拟代表有害突变发生在整个基因组（任意图长度R），探讨杂种优势的大小，其影响的扩散的演变。这些结果表明，杂种优势可能有重要的影响扩散时，它是在自然群体中观察到的值的上限范围内，这发生在我们的模拟时，基因组有害突变率U也在观察值的上限范围。将结果与分析型双位点模型的外推结果进行比较表明，当U值不太高（大致为U <0.5）时，杂种优势的影响主要由影响扩散的位点与选定位点之间的成对关联驱动，而高阶关联对于U值较高变得重要。
When dispersal is limited, crosses between different regions may generate progeny of higher fitness than crosses within regions, due to the fact that individuals from the same region are more likely to share the same recessive deleterious alleles. This phenomenon (termed heterosis) generates a selective force favouring dispersal; however, the importance of heterosis on dispersal evolution has been a subject for debate. In this paper, we use computer simulations representing deleterious mutations occurring over a whole genome (of arbitrary map length R) to explore the magnitude of heterosis, and its effect on the evolution of dispersal. These results show that heterosis may have important effects on dispersal when it is in the upper range of values observed in natural populations, which occurs in our simulations when the genomic deleterious mutation rate U is also in the upper range of observed values. Comparing the results with extrapolations from an analytical two‐locus model indicates that the effect of heterosis is mainly driven by pairwise associations between the locus affecting dispersal and selected loci when U is not too high (roughly, U < 0.5), whereas higher order associations become important for higher values of U.