Stage‐specific expression of two actin genes in the yellow fever mosquito, Aedes aegypti
Stage‐specific expression of two actin genes in the yellow fever mosquito, Aedes aegypti
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黄热病蚊子埃及伊蚊中两个肌动蛋白基因的阶段特异性表达
DOI：
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Q. Lan
中科院分区：
文献类型：
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作者：
I. Vyazunova;Q. Lan
研究了黄热病蚊子埃及伊蚊中两种肌肉特异性肌动蛋白基因的表达模式。 AeAct-2 的编码序列与果蝇和预测的冈比亚按蚊肌动蛋白基因的编码序列具有 82% 至 85% 的相似性。 AeAct-2 基因的转录在发育阶段受到差异性调节，幼虫中的表达水平较高，而蛹和成虫中的表达水平较低。 AeAct-2基因主要在头部和体壁组织中表达。直到 4 龄后期，AeAct-3 基因的转录物才能在幼虫中检测到，并且在雄性蛹和早期雄性成虫中水平升高。 AeAct-3基因的主要表达部位是胸组织。因此，AeAct-3 是第一个报道的蚊子雄性特异性肌动蛋白基因。
The expression patterns of two muscle‐specific actin genes were studied in the yellow fever mosquito, Aedes aegypti. The coding sequence of AeAct‐2 exhibits between 82 and 85% similarity with coding sequences of the Drosophila melanogaster and predicted Anopheles gambiae actin genes. The transcription of the AeAct‐2 gene was differentially regulated during developmental stages with higher levels of expression in larvae and lower levels in pupae and adults. The AeAct‐2 gene is mainly expressed in the head and body wall tissues. Transcripts of the AeAct‐3 gene are not detectable in larvae until late 4th instar and the level increased in male pupae and early male adults. The main site of expression of the AeAct‐3 gene was the thoracic tissue. Thus, AeAct‐3 is the first reported male‐specific actin gene in mosquitoes.
DOI：
10.1016/s0074-7696(08)61874-4
发表时间：
1993
期刊：
International review of cytology
影响因子：
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作者：
S. Bernstein;P. T. O'Donnell;R. Cripps
通讯作者：
S. Bernstein;P. T. O'Donnell;R. Cripps