Intranasal administration of oxytocin promotes social play in domestic dogs.
Intranasal administration of oxytocin promotes social play in domestic dogs.
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DOI：
10.1080/19420889.2015.1017157
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发表时间：
2015-05
影响因子：
--
通讯作者：
Kikusui T
中科院分区：
文献类型：
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作者：
Romero T;Nagasawa M;Mogi K;Hasegawa T;Kikusui T
在最近的一篇论文中，我们研究了在非生殖环境下，家养狗体内的催产素是否会调节亲密社会关系的维持。我们发现外源性催产素不仅促进了对同种动物的积极社会行为，而且也促进了对人类伴侣的积极社会行为。在这里，我们进一步详细研究了催产素操纵对社交游戏的影响。与喷洒生理盐水相比，喷洒催产素后，受试者更频繁地开始玩游戏，玩的时间也更长。此外，在鼻腔摄入催产素后，狗比生理盐水后更频繁地显示游戏信号，这表明催产素增强了狗的游戏动机。据我们所知，这项研究首次提供了催产素促进家狗社交游戏的证据。我们利用这些结果来假设催产素在促进社会行为和治疗家养狗的社会缺陷方面的潜在治疗用途。
In a recent paper, we examined whether oxytocin in the domestic dog modulates the maintenance of close social bonds in non-reproductive contexts. We found that exogenous oxytocin promotes positive social behaviors not only toward conspecifics, but also toward human partners. Here we examined in further detail the effect that oxytocin manipulation has on social play. When sprayed with oxytocin, subjects initiated play sessions more often and played for longer periods of time than when sprayed with saline. Furthermore, after oxytocin nasal intake dogs displayed play signals more often than after saline administration, suggesting that oxytocin enhances dogs' play motivation. To our knowledge, this study provides the first evidence that oxytocin promotes social play in the domestic dog. We use these results to hypothesize on the potential therapeutic use of oxytocin for promoting social behaviors and treating social deficits in the domestic dog.