Continuous ASL (CASL) perfusion MRI with an array coil and parallel imaging at 3T
Continuous ASL (CASL) perfusion MRI with an array coil and parallel imaging at 3T
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DOI：
10.1002/mrm.20574
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发表时间：
2005-09-01
影响因子：
3.3
通讯作者：
Detre, JA
中科院分区：
文献类型：
--
作者：
Wang, Z;Wang, JJ;Detre, JA
本研究的目的是评估在连续动脉自旋标记（CASL）灌注MRI中使用阵列线圈和并行成像的可行性和有效性。8通道仅接收阵列头部线圈与周围的可解调体积发射线圈结合使用。信噪比（SNR），时间稳定性，脑血流量（CBF），和灌注图像覆盖范围进行了测量，从稳态CASL扫描使用：一个标准的体积线圈，阵列线圈，阵列线圈与2和3倍加速并行成像。与标准体积线圈相比，阵列线圈提供了3倍的平均SNR增加和更高的时间稳定性的灌注加权图像，即使有三倍的加速。尽管阵列线圈的灌注图像受到不均匀线圈灵敏度的影响，但这种影响在定量CBF图像中是不可见的，与标准体积线圈相比，定量CBF图像显示出高度可重复的灌注值。并行成像的展开失真在灌注图像中被成对减影抑制，尽管它们使原始EPI图像急剧退化。此外，由于缩短了采集时间并改善了具有高静态场不均匀性的大脑区域的覆盖范围，并行成像提供了采集更多切片的可能性。这些结果突出了阵列线圈和并行成像在ASL灌注MRI中的潜在效用。
The purpose of this work was to assess the feasibility and efficacy of using an array coil and parallel imaging in continuous arterial spin labeling (CASL) perfusion MRI. An 8-channel receive-only array head coil was used in conjunction with a surrounding detunable volume transmit coil. The signal to noise ratio (SNR), temporal stability, cerebral blood flow (CBF), and perfusion image coverage were measured from steady state CASL scans using: a standard volume coil, array coil, and array coil with 2- and 3-fold accelerated parallel imaging. Compared to the standard volume coil, the array coil provided 3 times the average SNR increase and higher temporal stability for the perfusion weighted images, even with threefold acceleration. Although perfusion images of the array coil were affected by the inhomogeneous coil sensitivities, this effect was invisible in the quantitative CBF images, which showed highly reproducible perfusion values compared to the standard volume coil. The unfolding distortions of parallel imaging were suppressed in the perfusion images by pairwise subtraction, though they sharply degraded the raw EPI images. Moreover, parallel imaging provided the potential of acquiring more slices due to the shortened acquisition time and improved coverage in brain regions with high static field inhomogeneity. Such results highlight the potential utility of array coils and parallel imaging in ASL perfusion MRI.