The neural sources of N170: Understanding timing of activation in face-selective areas
The neural sources of N170: Understanding timing of activation in face-selective areas
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DOI：
10.1111/psyp.13336
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发表时间：
2019-06-01
期刊：
影响因子：
3.7
通讯作者：
Hanayik, Taylor
中科院分区：
文献类型：
--
作者：
Gao, Chuanji;Conte, Stefania;Hanayik, Taylor
N170 ERP成分被广泛认为是面部敏感的神经标记。尽管对N170的神经来源进行了广泛的研究，但在以前的文献中存在两个问题：（a）很少有研究使用个体化解剖结构作为N170皮质来源分析的头部模型;（B）N170与fMRI研究中面部选择区域之间的关系尚不清楚。在这里，我们通过向同一组健康成年人展示人脸和房屋的图片，并在不同的时间段记录结构MRI，fMRI和高密度ERPs来解决这些问题。根据参与者的解剖结构进行的源分析表明，中间和后部梭状回是N170面部敏感方面的主要神经源。基于fMRI感兴趣区域的源分析显示，fMRI定义的梭状面区是N170的主要贡献者。目前的研究表明，梭状回是一个主要的神经贡献者的N170 ERP组件，并提供了进一步的见解的时空特征的面孔处理。
The N170 ERP component has been widely identified as a face-sensitive neural marker. Despite extensive investigations conducted to examine the neural sources of N170, there are two issues in prior literature: (a) few studies used individualized anatomy as head model for the cortical source analysis of the N170, and (b) the relationship between the N170 and face-selective regions from fMRI studies is unclear. Here, we addressed these questions by presenting pictures of faces and houses to the same group of healthy adults and recording structural MRI, fMRI, and high-density ERPs in separate sessions. Source analysis based on the participant's anatomy showed that the middle and posterior fusiform gyri were the primary neural sources for the face-sensitive aspects of the N170. Source analysis based on regions of interest from the fMRI revealed that the fMRI-defined fusiform face area was the major contributor to the N170. The current study suggests that the fusiform gyrus is a major neural contributor to the N170 ERP component and provides further insights about the spatiotemporal characteristics of face processing.