Impact of continuous positive airway pressure (CPAP) on quality of life in patients with obstructive sleep apnea (OSA).
Impact of continuous positive airway pressure (CPAP) on quality of life in patients with obstructive sleep apnea (OSA).
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DOI：
10.1111/jsr.12430
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发表时间：
2016-12
影响因子：
4.4
通讯作者：
Quan SF
中科院分区：
文献类型：
--
作者：
Batool-Anwar S;Goodwin JL;Kushida CA;Walsh JA;Simon RD;Nichols DA;Quan SF
阻塞性睡眠呼吸暂停是一种慢性疾病，发病率不断上升。除了相关的心血管合并症外，阻塞性睡眠呼吸暂停综合征还与生活质量差、职业事故和继发于日间过度嗜睡的机动车碰撞有关。虽然持续气道正压通气是睡眠呼吸暂停治疗的金标准，但其对生活质量的影响尚未明确。在本研究中，我们使用来自呼吸暂停正压通气长期疗效研究（APPLES）的一个子集的数据调查了治疗对生活质量的影响，APPLES是一项持续气道正压通气（CPAP）与假CPAP的随机对照试验。卡尔加里睡眠呼吸暂停生活质量指数（SAQLI）用于评估生活质量。我们发现，对于患有严重和可能中度睡眠呼吸暂停的人来说，使用CPAP可以长期改善生活质量。然而，轻度阻塞性睡眠呼吸暂停患者的生活质量没有明显改善。
Obstructive Sleep Apnea is a chronic illness with increasing prevalence. In addition to associated cardiovascular comorbidities, obstructive sleep apnea syndrome has been linked to poor quality life, occupational accidents, and motor vehicle crashes secondary to excessive daytime sleepiness. Although continuous positive airway pressure is the gold standard for sleep apnea treatment, its effects on quality of life are not well defined. In the current study we investigated the effects of treatment on quality of life using the data from a subset of the Apnea Positive Pressure Long-term Efficacy Study (APPLES), a randomized controlled trial of continuous positive airway pressure (CPAP) vs. sham CPAP. The Calgary Sleep Apnea Quality of Life Index (SAQLI) was used to assess quality of life. We found that long-term improvement in quality of life occurs with the use of CPAP in persons with severe and possibly moderate sleep apnea. However no demonstrable improvement in quality of life was noted among participants with mild obstructive sleep apnea.