Imperceptible senescence:: Ageing in the ocean quahog Arctica islandica
Imperceptible senescence:: Ageing in the ocean quahog Arctica islandica
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DOI：
10.1080/10715760802108849
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发表时间：
2008-05-01
影响因子：
3.3
通讯作者：
Philipp, Eva E. R.
中科院分区：
文献类型：
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作者：
Abele, Doris;Strahl, Julia;Philipp, Eva E. R.
海洋quahog Arctica islandica是地球上所有双壳类和软体动物物种中寿命最长的。超过100岁的动物很常见，据报道，冰岛周围的最大寿命接近400岁。高和稳定的抗氧化能力是一种可能的策略，以减缓衰老和延长寿命，这项研究调查了几个抗氧化参数和线粒体标记酶的寿命范围从4-200年的冰岛quahog。在4-192年龄的A. islandica，过氧化氢酶，柠檬酸合酶活性和谷胱甘肽浓度在前25年内迅速下降，涵盖了快速体细胞生长和性成熟到过度发育成熟阶段的过渡阶段（~ 32年）。此后，所有这三个参数在150年以上的时间里保持相当稳定的水平。与此相反，超氧化物歧化酶的活动在整个生命周期保持高水平。这些结果支持了“自由基-生存率理论”，A。islandica是非常高的，因此可以解释物种的寿命长。
The ocean quahog Arctica islandica is the longest-lived of all bivalve and molluscan species on earth. Animals over 100 years are common and reported maximum live span around Iceland is close to 400 years. High and stable antioxidant capacities are a possible strategy to slow senescence and extend lifespan and this study has investigated several antioxidant parameters and a mitochondrial marker enzyme in a lifetime range spanning from 4-200 years in the Iceland quahog. In gill and mantle tissues of 4-192 year old A. islandica, catalase, citrate synthase activity and glutathione concentration declined rapidly within the first 25 years, covering the transitional phase of rapid somatic growth and sexual maturation to the outgrown mature stages (- 32 years). Thereafter all three parameters kept rather stable levels for > 150 years. In contrast, superoxide dismutase activities maintained high levels throughout life time. These findings support the 'Free Radical-Rate of Living theory', antioxidant capacities of A. islandica are extraordinarily high and thus may explain the species long life span.