Optically Induced Nanostructures: Biomedical and Technical Applications-猫眼课题宝

DOI：

10.1515/9783110354324

发表时间：

2015-01

期刊：

影响因子：

通讯作者：

中科院分区：

其他

文献类型：

作者：

K. König;A. Ostendorf

中心波长为800纳米的紧聚焦85 MHz重复频率亚15飞秒脉冲激光有助于对各种材料进行亚微米和纳米级的加工。利用双光子光刻技术制备了三维聚合物结构，并将其应用于细胞培养基质。在SU-8上制作了边缘小于100 nm的锥形毛细管，用于电喷雾电离。氧化铟锡(ITO)纳米线是亚烧蚀阈值下的重结晶和随后在盐酸中刻蚀的产物。玻璃上的纳米线被用作气体传感器，而独立的纳米线则作为共振频率在兆赫范围内的谐振器。激光诱导的周期性表面结构(LIPSS)以200 nm以下的周期在单晶硅表面和ITO薄膜中形成，片上产生的周期性纳米管增加了ITO多电极阵列的有效面积。为了便于液晶(LC)的对准，利用亚15fLIPSS对ITO薄膜电极进行了图案化。用有限元方法对器件的结构和性能进行了研究。1.1激光显微镜--用于成像、操作、材料表征以及显微和纳米加工的通用工具激光显微镜已经存在了50多年。1962年，也就是激光发明两年后，贝西斯等人。报道了红宝石激光显微镜用于暴露细胞器的应用[1]。同年，Brech和Cross实现了材料的微发射，并引入了激光诱导击穿光谱(LIBS)[2]。此外，LIBS仪器还被JarrellAsh公司商业化。先进的激光显微镜LMA 1是由VEB Carl Zeiss Jena于1964年开发的，并于1965年在莱比锡春季博览会上展出。相比之下，今天的显微镜的大多数应用都集中在材料和生物标本的非破坏性3D成像上。第一台激光扫描成像显微镜是明斯基共焦显微镜的进一步发展，由Davidovits和Egger于1969年使用5 mW氦-霓虹灯[3]建造。诸如共焦激光扫描显微镜之类的传统激光显微镜使用紫外线(UV)和可见光(VIS)激光辐射。激光显微镜也被用作光学操纵工具，如激光镊子[4，5]。©2015 K.König等人，由de Gruyter出版。本作品受知识共享署名-非商业性-NoDerivs3.0许可证许可。

Tightly focused 85MHz repetition rate sub-15 femtosecond pulsed laser light of a central wavelength at 800nm facilitates submicron and nanoscale processing of a large variety of materials. Three-dimensional polymer structures were generated by two-photon lithography and applied as cell culture substrates. Conically shaped capillaries with sub-100nm edges were produced in SU-8 for electrospray ionization. Indium tin oxide (ITO) nanowires resulted from recrystallization on sub-ablation threshold exposure and subsequent etching in hydrochloric acid. Nanowires on glass were applied as gas sensors, whereas free-standing nanowires acted as resonators with resonance frequencies in themegahertz range. Laser-induced periodic surface structures (LIPSS)were generated on crystalline silicon surfaces and in thin ITOfilms at periodicities below200nm.Periodic nanocuts producedon-chip increased the effective area of ITOmulti-electrode arrays. ITO thin-film electrodes for liquid crystal (LC) applications were patterned by sub-15 fs LIPSS in order to facilitate LC alignment. The properties of the structures and the performance of the devices were investigated using the finiteelement method. 1.1 Laser microscopes – universal tools for imaging, manipulation, material characterization, and microand nanoprocessing Laser microscopes have existed for more than 50 years. In 1962, just two years after the invention of the laser, Bessis et al. reported on the use of a ruby laser microscope applied to expose cell organelles [1]. In the same year, Brech and Cross achieved a microemission of materials and introduced laser-induced breakdown spectroscopy (LIBS) [2]. Moreover, the LIBS instrument was commercialized by the company JarrellAsh. An advanced laser microscope LMA 1 was developed by VEB Carl Zeiss Jena in 1964 and presented in 1965 at the Leipzig Spring Fair. In contrast,most of the applications of today’smicroscopes focus onnon-destructive 3D imaging of materials and biological specimens. The first laser scanning imaging microscope, a further development of a Minsky confocal microscope, was built by Davidovits and Egger in 1969 using a 5mW helium-neon laser [3]. Conventional laser microscopes such as confocal laser scanning microscopes employ ultraviolet (UV) and visible (VIS) laser radiation. Laser microscopes have also been used as optical manipulation tools such as laser tweezers [4, 5]. © 2015 K. König et al., published by De Gruyter. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.

Optically Induced Nanostructures: Biomedical and Technical Applications

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