Cancer Diagnostic Delay in Northern and Central Italy During the 2020 Lockdown Due to the Coronavirus Disease 2019 Pandemic Assessment of the Magnitude of the Problem and Proposals for Corrective Actions

Cancer Diagnostic Delay in Northern and Central Italy During the 2020 Lockdown Due to the Coronavirus Disease 2019 Pandemic Assessment of the Magnitude of the Problem and Proposals for Corrective Actions
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DOI:
10.1093/ajcp/aqaa177
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发表时间:
2021-01-01
影响因子:
3.5
通讯作者:
Saragoni, Luca
Saragoni, Luca
中科院分区:
医学4区
文献类型:
--
作者:
Ferrara, Gerardo;De Vincentiis, Ludovica;Saragoni, Luca

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目的:我们进行了有关2019年冠状病毒病的数据收集(COVID-19)大流行相关的癌症诊断延迟,以个性化适当的纠正程序。方法:比较了2018年第11周至20周首次病理诊断为恶性肿瘤的人数,2019年,结果:与2018年和2019年记录的平均数量相比,2020年的癌症诊断下降了44.9%。黑色素瘤和非黑色素瘤皮肤癌占所有漏诊的56.7%。结直肠癌的诊断率下降(-46.6%)、前列腺(-45%)和膀胱(-43.6%)癌症在内部恶性肿瘤中最相关;然而,对于前列腺,高级别肿瘤仅受到中度影响结论:封锁对皮肤恶性肿瘤的诊断影响最大;在内部恶性肿瘤中,结肠直肠癌和浸润性膀胱癌最需要采取纠正措施。
Objectives: We performed data collection concerning the coronavirus disease 2019 (COVID-19) pandemic-related delay in the diagnosis of cancers to individuate proper corrective procedures.Methods: A comparison was made among the number of first pathologic diagnoses of malignancy made from weeks 11 to 20 of 2018, 2019, and 2020 at seven anatomic pathology units serving secondary care hospitals in northern-central Italy.Results: Cancer diagnoses fell in 2020 by 44.9% compared with the average number recorded in 2018 and 2019. Melanoma and nonmelanoma skin cancer represented 56.7% of all missing diagnoses. The diagnostic decrease in colorectal (-46.6%), prostate (-45%), and bladder (-43.6%) cancer was the most relevant among internal malignancies; for prostate, however, high-grade tumors were only moderately affected (-21.7%).Conclusions: Diagnosis of cutaneous malignancies was mostly affected by the lockdown; among internal malignancies, corrective actions were mostly needed for colorectal cancer and invasive bladder cancer.