Pregnancy‐induced hypertension in twin pregnancy
Pregnancy‐induced hypertension in twin pregnancy
复制标题
双胎妊娠妊娠高血压综合征
DOI：
10.1111/j.1471-0528.1984.tb04760.x
复制
发表时间：
1984
期刊：
影响因子：
--
通讯作者：
M. Marivate
中科院分区：
文献类型：
--
作者：
P. F. McMULLAN;Robert J. Norman;M. Marivate
一项对德班 54 例初孕双胎妊娠的前瞻性研究表明，37% 的妊娠高血压患者发生妊娠高血压。这是非洲黑人人口中单胎妊娠预期率的两倍多。与年龄和胎次匹配的血压正常对照组患者相比，妊娠高血压患者组出生的婴儿明显体重更轻，胎儿生长迟缓率更高。通过 HLA 分型鉴定的同卵双胞胎在妊娠高血压组中的发生率明显高于对照组。提出了这一发现的可能的免疫学解释。
A prospective study of 54 primigravid twin pregnancies in Durban showed that pregnancy‐induced hypertension occurred in 37%. This was more than twice the expected rate for singleton pregnancies in this Black African population. The babies born in the group of patients with pregnancy‐induced hypertension were significantly lighter and had a higher rate of fetal growth retardation than the babies born in a normotensive control group of patients matched for age and parity. Monozygotic twins, identified by HLA typing, occurred significantly more often in the group with pregnancy‐induced hypertension than in the control group. A possible immunological explanation for this finding is presented.