Prolonged bleeding time in children and young adults with hemophilia.
Prolonged bleeding time in children and young adults with hemophilia.
复制标题
患有血友病的儿童和年轻人出血时间延长。
DOI：
10.1097/01241398-198110000-00042
复制
发表时间：
1980
期刊：
影响因子：
8
通讯作者：
C. Holtkamp
中科院分区：
文献类型：
--
作者：
G. Buchanan;C. Holtkamp
在49例至少72小时未接受置换输血的血友病A或B患者中，10例出血时间延长。没有人有血管性血友病或既往服用阿司匹林的证据，只有一人被发现有相关的内在血小板缺陷。出血时间通常被认为是血小板-内皮下相互作用的量度，在血小板功能正常的先天性凝血障碍中，出血时间有时也可能延长。
Of 49 patients with hemophilia A or B, who had not received replacement transfusions for at least 72 hours, ten were demonstrated to have a prolonged value for the bleeding time. None had evidence of von Willebrand's disease or prior aspirin ingestion, and only one was found to have an associated intrinsic platelet defect. It appears that the bleeding time, generally thought to be a measurement of platelet-subendothelium interaction, may also sometimes be prolonged in congenital coagulation disorders in which platelet function is normal.