Terahertz pulsed spectroscopy of paraffin-embedded brain glioma
Terahertz pulsed spectroscopy of paraffin-embedded brain glioma
复制标题
石蜡包埋脑胶质瘤的太赫兹脉冲光谱
DOI：
10.1117/1.jbo.19.7.077001
复制
发表时间：
2014-07-01
影响因子：
3.5
通讯作者：
Zhao, Jian-heng
中科院分区：
文献类型：
--
作者：
Meng, Kun;Chen, Tu-nan;Zhao, Jian-heng
抽象的。用太赫兹时域谱系统测量了石蜡包埋的脑胶质瘤和正常脑组织在0.2~2.0太赫兹范围内的折射率、吸收系数和复介电常数。得到了人脑胶质瘤与正常脑组织的光谱差异。与正常脑组织相比，我们的结果表明石蜡包埋的脑胶质瘤具有更高的折射率、吸收系数和介电常数。在此基础上，分析了石蜡包埋脑胶质瘤的不同成像方法，如强度成像、连续太赫兹源相干成像和短脉冲太赫兹脉冲成像的最佳太赫兹频率。
Abstract. The refractive indices, absorption coefficients, and complex dielectric constants of paraffin-embedded brain glioma and normal brain tissues have been measured by a terahertz time-domain spectroscopy (THz-TDS) system in the 0.2- to 2.0-THz range. The spectral differences between gliomas and normal brain tissues were obtained. Compared with normal brain tissue, our results indicate that paraffin-embedded brain gliomas have a higher refractive index, absorption coefficient, and dielectric constant. Based on these results, the best THz frequencies for different methods of paraffin-embedded brain glioma imaging, such as intensity imaging, coherent imaging with continuum THz sources, and THz pulsed imaging with short-pulsed THz sources, are analyzed.