A Chiral [3]Rotaxane Comprising Achiral Bis-macrocyclic and Dumbbell-Shaped Components
A Chiral [3]Rotaxane Comprising Achiral Bis-macrocyclic and Dumbbell-Shaped Components
复制标题
一种包含非手性双大环和哑铃形组分的手性[3]轮烷
DOI：
10.1021/acs.orglett.1c00271
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发表时间：
2021
期刊：
影响因子：
5.2
通讯作者：
Tokunaga Yuji
中科院分区：
文献类型：
--
作者：
Morise Takaaki;Muranaka Atsuya;Ban Hayato;Harada Mei;Naito Masaya;Yoshida Kazuyuki;Kobayashi Nagao;Uchiyama Masanobu;Tokunaga Yuji
在这项研究中，我们合成了一种分子手性[3]轮烷，其包含一个杯双冠醚（作为大环组分）和两个不对称的二烷基铵盐（作为哑铃形组分），其中任何单个组分都没有任何手性。手性高效液相色谱法用于分离对映体，其特征在于圆二色谱。密度泛函理论计算给出了对每个[3]轮烷的绝对构型的洞察。
In this study, we synthesized a molecularly chiral [3]rotaxane comprising a calix-bis-crown ether (as the macrocyclic component) and two unsymmetrical dialkylammonium salts (as dumbbell-shaped components) without any chirality in any of the individual components. Chiral high-performance liquid chromatography was used to separate the enantiomers, which were characterized by circular dichroism spectroscopy. Density functional theory calculations gave an insight into the absolute configuration of each [3]rotaxane.