Effects of long-term potentiation in the human visual cortex: a functional magnetic resonance imaging study

Effects of long-term potentiation in the human visual cortex: a functional magnetic resonance imaging study
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DOI:
10.1097/00001756-200512190-00001
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发表时间:
2005-12-19
期刊:
影响因子:
1.7
通讯作者:
Jancke, L
Jancke, L
中科院分区:
医学4区
文献类型:
--
作者:
Clapp, WC;Zaehle, T;Jancke, L

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应用功能性磁共振成像技术,缓慢闪烁的棋盘格(0.25 Hz)引起的血流动力学反应进行了测量之前和之后的快速呈现的棋盘格(9 Hz -一个“光强直”)块交付。先前已经用脑电图显示,这种光强直增强视觉诱发电位的成分。在本研究中,在纹外视皮层的血流动力学反应显着增加,以低频率的棋盘后,光破伤风管理。这些结果支持了长时程增强可以在人类视觉皮层内非侵入性地证明的观点,并提供了塑性变化位于次级视觉皮层内的证据。神经报告16:1977-1980(c)2005 Lippincott威廉姆斯&威尔金斯。
Applying functional magnetic resonance imaging techniques, hemodynamic responses elicited by slowly flashing checkerboards (0.25 Hz) were measured both before and after a block of rapidly presented checkerboards (9 Hz - a 'photic tetanus') was delivered. It has been shown previously, using electroencephelography, that this photic tetanus potentiates components of the visual-evoked potential. In the present study, hemodynamic responses in the extrastriate visual cortex were significantly increased to checkerboards presented at a low frequency after the administration of the photic tetanus. These results support the idea that long-term potentiation can be demonstrated non-invasively within the human visual cortex and provide evidence that the plastic changes are localized within the secondary visual cortex. NeuroReport 16:1977-1980 (c) 2005 Lippincott Williams & Wilkins.