Comparison of choroidal thicknesses using swept source and spectral domain optical coherence tomography in diseased and normal eyes
Comparison of choroidal thicknesses using swept source and spectral domain optical coherence tomography in diseased and normal eyes
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DOI：
10.1136/bjophthalmol-2014-305331
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发表时间：
2015-03-01
影响因子：
4.1
通讯作者：
Cheong, Kai Xiong
中科院分区：
文献类型：
--
作者：
Tan, Colin S. H.;Ngo, Wei Kiong;Cheong, Kai Xiong
背景/目标 据报道，脉络膜厚度测量在扫频光学相干断层扫描 (SS-OCT) 和谱域 OCT (SD-OCT) 之间存在差异。本研究旨在评估使用 SS-OCT 和 SD-OCT 设备测量视网膜疾病患者和正常参与者的脉络膜厚度的可比性。 方法 在一项 100 名受试者（包括视网膜疾病患者和正常志愿者）的前瞻性队列研究中，使用标准化成像协议使用 DRI OCT-1 和 Spectralis OCT 依次进行 OCT 扫描。中心凹下脉络膜厚度由蒙面阅读中心认证的分级师独立测量。使用配对 t 检验和组内相关系数 (ICC) 来比较测量结果。 结果 在所有 100 名参与者中，DRI OCT-1 和 Spectralis OCT 的平均中心凹下脉络膜厚度分别为 264.3 μm 和 272.4 μm (p=0.001)，ICC 为 0.989。与正常眼睛相比，患有视网膜疾病的眼睛在 OCT 设备之间脉络膜厚度的平均差异更大（8.4 μm vs 7.3 μm）。眼睛脉络膜厚度
Background/aims Choroidal thickness measurements are reported to differ between swept source optical coherence tomography (SS-OCT) and spectral domain OCT (SD-OCT). This study aimed to assess the comparability of choroidal thickness measurements using SS-OCT and SD-OCT devices among patients with retinal diseases and normal participants.Methods In a prospective cohort study of 100 subjects, comprising patients with retinal disease and normal volunteers, OCT scans were performed sequentially with the DRI OCT-1 and Spectralis OCT using standardised imaging protocols. Subfoveal choroidal thicknesses were independently measured by masked reading-centre certified graders. Paired t tests and intraclass correlation coefficients (ICCs) were used to compare the measurements.Results Among all 100 participants, mean subfoveal choroidal thickness was 264.3 mu m and 272.4 mu m for DRI OCT-1 and Spectralis OCT respectively (p=0.001), with ICC of 0.989. The mean difference in choroidal thickness between OCT devices was larger among eyes with retinal diseases compared with normal eyes (8.4 mu m vs 7.3 mu m). Eyes with choroidal thickness