Protein intake and lean body mass preservation during energy intake restriction in overweight older adults
Protein intake and lean body mass preservation during energy intake restriction in overweight older adults
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DOI：
10.1038/ijo.2015.182
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发表时间：
2016-02-01
影响因子：
4.9
通讯作者：
de Groot, L. C. P. G. M.
中科院分区：
文献类型：
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作者：
Backx, E. M. P.;Tieland, M.;de Groot, L. C. P. G. M.
背景：饮食诱导的体重减轻通常伴随着骨骼肌质量的下降。肌肉质量的损失导致肌肉力量下降，并损害身体表现。研究目的：探讨在12周的能量摄入限制期间，增加膳食蛋白质摄入量对超重老年人瘦体重、力量和体能的影响。设计：61名超重和肥胖的男女（63 +/- 5岁）被随机分配到高蛋白饮食（HP; 1.7 g kg（-1）/天; n = 31）或正常蛋白质饮食（NP; 0.9 g kg（-1）/天; n = 30）。在控制饮食干预期间，90%的饮食由大学提供。在基线和干预后，体重、瘦体重（双能X线吸收法），腿部力量（最多重复1次），体能（短期体能测试，400米）和习惯性体力活动结果：两组的体重均下降，HP组和NP组之间无差异（分别为-8.9 +/- 2.9和-9.1 +/- 3.4 kg; P = 0.584）。瘦体重分别下降1.8 +/- 2.2和2.1 +/- 1.4 kg，组间无显著差异（P = 0.213）。干预期间腿部力量下降了8.8 +/- 14.0和8.9 +/- 12.8 kg，组间无差异（P = 0.689）。通过400米步行速度测量，两组的身体表现都有所改善，两组之间没有差异（P = 0.219）。结论：在超重老年人长期限制能量摄入期间，增加蛋白质摄入量超过习惯摄入水平（每天0.9 g kg（-1））并不能保持瘦体重、力量或身体表现。
BACKGROUND: Dietary-induced weight loss is generally accompanied by a decline in skeletal muscle mass. The loss of muscle mass leads to a decline in muscle strength and impairs physical performance. A high dietary protein intake has been suggested to allow muscle mass preservation during energy intake restriction.OBJECTIVE: To investigate the impact of increasing dietary protein intake on lean body mass, strength and physical performance during 12 weeks of energy intake restriction in overweight older adults.DESIGN: Sixty-one overweight and obese men and women (63 +/- 5 years) were randomly assigned to either a high protein diet (HP; 1.7 g kg(-1) per day; n = 31) or normal protein diet (NP; 0.9 g kg(-1) per day; n = 30) during a 12-week 25% energy intake restriction. During this controlled dietary intervention, 90% of the diet was provided by the university. At baseline and after the intervention, body weight, lean body mass (dual-energy X-ray absorptiometry), leg strength (1-repetition maximum), physical performance (Short Physical Performance Battery, 400 m) and habitual physical activity (actigraph) were assessed.RESULTS: Body weight declined in both groups with no differences between the HP and NP groups (-8.9 +/- 2.9 versus -9.1 +/- 3.4 kg, respectively; P = 0.584). Lean body mass declined by 1.8 +/- 2.2 and 2.1 +/- 1.4 kg, respectively, with no significant differences between groups (P = 0.213). Leg strength had decreased during the intervention by 8.8 +/- 14.0 and 8.9 +/- 12.8 kg, with no differences between groups (P = 0.689). Physical performance as measured by 400 m walking speed improved in both groups, with no differences between groups (P = 0.219).CONCLUSIONS: Increasing protein intake above habitual intake levels (0.9 g kg(-1) per day) does not preserve lean body mass, strength or physical performance during prolonged energy intake restriction in overweight older adults.