Marital status and risk of out-of-hospital sudden cardiac arrest in the population
Marital status and risk of out-of-hospital sudden cardiac arrest in the population
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DOI：
10.1097/hjr.0b013e3283083e04
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发表时间：
2008-10-01
影响因子：
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通讯作者：
Siscovick, David
中科院分区：
文献类型：
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作者：
Empana, Jean-Philippe;Jouven, Xavier;Siscovick, David
背景我们最近报道了临床抑郁与院外心脏骤停(SCA)之间的关系。在这项研究中，我们通过研究婚姻状况和院外SCA之间的关系，扩展了我们对心理社会特征对SCA的贡献的研究。设计了一项关于突发SCA危险因素的大型病例对照研究，包括2119例病例和4042例匹配对照。1980~1994年间6例(平均年龄67岁)发生SCA。对照组是参与者的分层随机样本，按年龄、性别、早期心脏病和日历年定义。使用门诊护理医疗记录评估SCA或对照的可比指数日期时的婚姻状况。结果与对照组相比，未婚(30.2%比21.0%)、分居或离婚(10.0%比70%)、单身(5.0%比3.6%)和丧偶(15.2%比10.4%)更容易发生。调整SCA危险因素后，未婚参与者患SCA的风险更高(优势比：1.53；95%可信区间：1.33-1.76)。根据性别、较大年龄(>；70岁)、早期冠心病和临床抑郁的存在观察到一致的结果。既未婚又临床抑郁的人患SCA的风险最高。结论这些数据支持婚姻状况与SCA之间的关联。EUJ心脏康复15：577-582(C)2008欧洲心脏病学会
Background We have recently reported on the association between clinical depression and out-of-hospital sudden cardiac arrest (SCA). In this study, we extend our research on the contribution of psychosocial characteristics to SCA, by examining the association between marital status and out-of-hospital SCA.Design A large case-control study of risk factors for incident SCA including 2119 cases and 4042-matched controls.Methods Participants were enrollees of a health maintenance organization (USA). Cases experienced SCA between 1980 and 1994 (mean age of 67 years). Controls were a stratified random sample of enrollees, with the strata defined by age, sex, earlier heart disease, and calendar year. The marital status at the time of the SCA or a comparable index date for controls was assessed using ambulatory care medical records. Conditional logistic regression was used to estimate odds ratio and its 95% confidence interval.Results Cases were more likely to be unmarried than the controls (30.2% vs. 21.0%), defined as being separated or divorced (10.0% vs. 70%), single (5.0% vs. 3.6%) or widowed (15.2% vs. 10.4%). Unmarried participants had a higher risk of SCA (odds ratio: 1.53; 95% confidence interval: 1.33-1.76), after adjustment for SCA risk factors. Consistent findings were observed according to sex, older age (>70 years), earlier coronary heart disease and the presence of clinical depression. Those who were both unmarried and clinically depressed had the highest risk of SCA.Conclusion These data support an association between marital status and SCA. Eur J Cardiovasc Prev Rehabil 15:577-582 (C) 2008 The European Society of Cardiology