Synthesis of Enantiomerically Pure and Racemic Benzyl-Tethered Ru(II)/TsDPEN Complexes by Direct Arene Substitution: Further Complexes and Applications
Synthesis of Enantiomerically Pure and Racemic Benzyl-Tethered Ru(II)/TsDPEN Complexes by Direct Arene Substitution: Further Complexes and Applications
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DOI：
10.1021/acs.organomet.7b00731
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发表时间：
2018-01
期刊：
影响因子：
2.8
通讯作者：
R. Soni;Katherine E. Jolley;S. Gosiewska;G. Clarkson;Z. Fang;T. H. Hall;Ben N. Treloar;Richard C. Knighton;M. Wills
中科院分区：
文献类型：
--
作者：
R. Soni;Katherine E. Jolley;S. Gosiewska;G. Clarkson;Z. Fang;T. H. Hall;Ben N. Treloar;Richard C. Knighton;M. Wills
本文报道了用直接芳烃交换法合成用于不对称转移氢化反应的苄基栓系芳烃/Ru/TsDPEN配合物。还制备了一系列通过三碳直链连接的配合物。芳烃交换方法显著简化了这类催化剂的合成方法，并允许容易形成改性类似物。该方法还提供了一种外消旋催化剂的路线，用于一般的氢还原或转移氢化。
The use of a direct arene-exchange method for the synthesis of benzyl-tethered arene/Ru/TsDPEN complexes for use in asymmetric transfer hydrogenation is reported. A series of complexes tethered through a three-carbon linear chain was also prepared. The arene-exchange approach significantly simplifies the synthetic approach to this class of catalyst and permits the ready formation of modified analogues. The approach also provides a route to racemic catalysts for use in general reductions with either hydrogen or transfer hydrogenation.