RELATIONSHIP OF NECROSIS AND TUMOR BORDER TO LYMPH-NODE METASTASES AND 10-YEAR SURVIVAL IN CARCINOMA OF BREAST

RELATIONSHIP OF NECROSIS AND TUMOR BORDER TO LYMPH-NODE METASTASES AND 10-YEAR SURVIVAL IN CARCINOMA OF BREAST
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DOI:
10.1097/00000478-197803000-00005
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发表时间:
1978-01-01
影响因子:
5.6
通讯作者:
ABBEY, H
ABBEY, H
中科院分区:
医学1区
文献类型:
--
作者:
CARTER, D;PIPKIN, RD;ABBEY, H

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对330例乳腺浸润癌根治术后10年随访的病理结果进行了回顾性分析。有无坏死和肿瘤的i边界的性质是两个因素,在所有情况下都是可观察的。与无坏死的原发癌相比,癌坏死与较高的死亡率、较高的腋窝淋巴结转移发生率以及较高的腋窝淋巴结转移患者死亡率相关。肿瘤坏死和根部边界显示出显着更积极的行为比那些肿瘤圆形边界,没有坏死。
The pathologic findings of 330 patients with invasive carcinoma of the breast who were followed for 10 years after radical mastectomy was reviewed. The presence or absence of necrosis and the character of the i border of the tumor were two factors which were observable in all cases. Necrosis in the carcinoma was associated with a higher mortality rate, a higher incidence of axillary node metastases, and a higher mortality rate in patients with axillary node metastases than were primary carcinomas without necrosis. Tumors with necrosis and a root border showed significantly more aggressive behavior than did those tumors with a rounded border and no necrosis.