Fasting and energy intake influence bone turnover in lightweight male rowers.
Fasting and energy intake influence bone turnover in lightweight male rowers.
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DOI：
10.1123/ijsn.8.4.377
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发表时间：
1998-12
期刊：
影响因子：
--
通讯作者：
S. Talbott;S. Shapses
中科院分区：
文献类型：
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作者：
S. Talbott;S. Shapses
本研究的目的是调查急性 24 小时禁食与正常 24 小时饮食摄入对大学轻量级男性赛艇运动员骨转换指标的影响。骨转换通过血清骨钙素 (OC) 和吡啶鎓交联物（吡啶啉 [PYD¿ 和脱氧吡啶啉 ¿ DPD]）的尿液排泄来测量。禁食受试者 (F) (n = 14) 体重减轻了 1.7 +/- 0.5 kg，但非禁食受试者 (NF) (n = 13) 没有显着变化。禁食 24 小时后，F 中的 PYD 和 DPD 较低（分别为 14.1 +/- 2.2 和 5.2 +/- 0.7 nmol/mmol 肌酐），而 NF 则较低（分别为 16.4 +/- 3.6 和 6.0 +/- 0.8 nmol/mmol 肌酐）（p<.05）。与 NF (6.1 +/- 0.9 ng/ml) 相比，禁食还可降低 OC 水平 (4.8 +/- 0.4 ng/ml) (p<.01)。 NF 饮食摄入量的逐步回归分析表明，与其他营养素相比，能量摄入解释了 PYD (34%)、DPD (36%) 和骨钙素 (46%) 骨转换变化的大部分变化 (p<.05)。这些结果表明，禁食 24 小时后骨转换会减少，并表明膳食能量摄入在调节骨转换中发挥作用。
The purpose of this study was to investigate the influence of an acute 24-hr fast versus usual 24-hr dietary intake on markers of bone turnover in collegiate lightweight male rowers. Bone turnover was measured by serum osteocalcin (OC) and urinary excretion of pyridinium cross-links (pyridinoline [PYD¿ and deoxypyridinoline ¿DPD]). Fasting subjects (F) (n = 14) reduced body weight by 1.7 +/- 0.5 kg but there was no significant change among nonfasting subjects (NF) (n = 13). Following 24 hr of fasting, PYD and DPD were lower in F (14.1 +/- 2.2 and 5.2 +/- 0.7 nmol/mmol creatinine, respectively) compared to NF (16.4 +/- 3.6 and 6.0 +/- 0.8 nmol/mmol creatinine)(p<.05). Fasting also reduce OC levels (4.8 +/- 0.4 ng/ml) compared to NF (6.1 +/- 0.9 ng/ml) (p<.01). Stepwise regression analysis of NF dietary intake indicated that energy intake explained a greater portion of the variation in bone turnover for PYD (34%), DPD (36%), and oseocalcin (46%) compared to other nutrients (p<.05). These results indicate that bone turnover is reduced by 24 hr of fasting and suggest a role for dietary energy intake in regulating bone turnover.